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The Capital Region of Denmark - a part of Copenhagen University Hospital
E-pub ahead of print

Using an Evidence-Based Research approach before a new study is conducted to ensure value

Research output: Contribution to journalJournal articleResearchpeer-review

  1. More than one-third of Cochrane reviews had gift authors, whereas ghost authorship was rare

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Ecological momentary assessments (EMAs) did not improve responsiveness of patient-reported outcomes on quality of life

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Half of Cochrane reviews were published more than 2 years after the protocol

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Unlike ROC analysis, a new IRT method identified clinical thresholds unbiased by disease prevalence

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Evidence-Based Research Network
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Background and Objectives: There is considerable actual and potential waste in research. The aim of this article is to describe how using an evidence-based research approach before conducting a study helps to ensure that the new study truly adds value. Study Design and Setting: Evidence-based research is the use of prior research in a systematic and transparent way to inform a new study so that it is answering questions that matter in a valid, efficient, and accessible manner. In this second article of the evidence-based research series, we describe how to apply an evidence-based research approach before starting a new study. Results: Before a new study is performed, researchers need to provide a solid justification for it using the available scientific knowledge as well as the perspectives of end users. The key method for both is to conduct a systematic review of earlier relevant studies. Conclusion: Describing the ideal process illuminates the challenges and opportunities offered through the suggested evidence-based research approach. A systematic and transparent approach is needed to provide justification for and to optimally design a relevant and necessary new study.

Original languageEnglish
JournalJournal of Clinical Epidemiology
ISSN0895-4356
DOIs
Publication statusE-pub ahead of print - 25 Sep 2020

    Research areas

  • Clinical health research, Clinical trials, Evidence synthesis, Evidence-based research, Medical ethics, Research ethics, Systematic review

ID: 60963369