TY - JOUR
T1 - Use of Personal Care Products and Semen Quality
T2 - A Cross-Sectional Study in Young Danish Men
AU - Ugelvig Petersen, Kajsa
AU - Balkiss, Ahmad Mahmoud
AU - Hærvig, Katia Keglberg
AU - Bonde, Jens Peter Ellekilde
AU - Hougaard, Karin Sørig
AU - Toft, Gunnar
AU - Ramlau-Hansen, Cecilia Høst
AU - Tøttenborg, Sandra Søgaard
PY - 2020/9
Y1 - 2020/9
N2 - Personal care products (PCPs) may contain multiple chemicals capable of harming male reproductive function. The aim of this study was, therefore, to assess aggregated PCP exposure and potential associations with measures of semen quality in young men. Participants (n = 1058, age 18-21) were sampled among young men from the Danish National Birth Cohort (DNBC). Upon recruitment in 2017-2019, each man answered an online questionnaire and provided a semen sample. Exposure to 12 common types of PCPs was derived from the questionnaire, and the extent of use and co-use was analyzed. We applied a negative binomial regression model to estimate percentage differences in semen parameters between low, medium and high PCP exposure groups. All participants were exposed to at least one PCP more than once a week, resulting in a mean number (SD) of 5.3 (2.0) PCPs currently used. Most participants (92%) were also exposed to fragranced products on a weekly basis. Little association was observed between aggregated exposure to PCPs and sperm concentration, total sperm count, semen volume, sperm motility and morphology. Despite prevalent use of multiple PCPs, we found little indication of adverse effects of aggregated overall or fragranced PCP exposure on semen quality.
AB - Personal care products (PCPs) may contain multiple chemicals capable of harming male reproductive function. The aim of this study was, therefore, to assess aggregated PCP exposure and potential associations with measures of semen quality in young men. Participants (n = 1058, age 18-21) were sampled among young men from the Danish National Birth Cohort (DNBC). Upon recruitment in 2017-2019, each man answered an online questionnaire and provided a semen sample. Exposure to 12 common types of PCPs was derived from the questionnaire, and the extent of use and co-use was analyzed. We applied a negative binomial regression model to estimate percentage differences in semen parameters between low, medium and high PCP exposure groups. All participants were exposed to at least one PCP more than once a week, resulting in a mean number (SD) of 5.3 (2.0) PCPs currently used. Most participants (92%) were also exposed to fragranced products on a weekly basis. Little association was observed between aggregated exposure to PCPs and sperm concentration, total sperm count, semen volume, sperm motility and morphology. Despite prevalent use of multiple PCPs, we found little indication of adverse effects of aggregated overall or fragranced PCP exposure on semen quality.
KW - Cohort
KW - Cosmetics
KW - Epidemiology
KW - Male infertility
KW - Personal care products
KW - Reproductive health
KW - Semen quality
UR - http://www.scopus.com/inward/record.url?scp=85090848874&partnerID=8YFLogxK
U2 - 10.3390/TOXICS8030062
DO - 10.3390/TOXICS8030062
M3 - Journal article
C2 - 32842629
SN - 2305-6304
VL - 8
JO - Toxics
JF - Toxics
IS - 3
M1 - 62
ER -