Use of nucleoside (tide) analogues in patients with hepatitis B-related acute liver failure

Doan Y Dao, Emmanuel Seremba, Veeral Ajmera, Corron Sanders, Linda S Hynan, William M Lee, Acute Liver Failure Study Group, Frank Vinholt Schiødt

38 Citations (Scopus)

Abstract

The efficacy of nucleoside(tide) analogues (NA) in the treatment of acute liver failure due to hepatitis B virus (HBV-ALF) remains controversial. We determined retrospectively the impact of NAs in a large cohort of patients with HBV-ALF.
Original languageEnglish
JournalDigestive Diseases and Sciences
Volume57
Issue number5
Pages (from-to)1349-57
Number of pages9
ISSN0163-2116
DOIs
Publication statusPublished - 2012

Keywords

  • Adult
  • Aged
  • Antiviral Agents
  • Bilirubin
  • Female
  • Hepatic Encephalopathy
  • Hepatitis B
  • Hepatitis B virus
  • Humans
  • Liver Failure, Acute
  • Liver Transplantation
  • Male
  • Middle Aged
  • Nucleosides
  • Prothrombin Time
  • ROC Curve
  • Retrospective Studies
  • Severity of Illness Index
  • Survival Analysis
  • Transaminases
  • Treatment Outcome
  • Virus Replication

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