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Urinretention ved postoperativ smertebehandling med epidurale opioider.

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  • B J Hansen
  • J Rosenberg
  • J T Andersen
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The incidence of retention of urine in cases of postoperative epidural opioid analgesia varies from 15% to 90%. The extent to which this phenomenon depends upon the dosage employed has not been elucidated. The cause of postoperative retention of urine (PU) is probably a combination of the central and peripheral effect of the opiate involving altered autonomic activity. Increased sympathetic activity resulting from surgery may, similarly, be a pathogenetic factor. The current methods of treatment are prophylactic or symptomatic alpha-receptor blockade, naloxon in refractory doses or catheterization. Inhibition of per- and postoperatively increased sympathetic activity may possibly prevent PU. Carbacholine is not effective in the treatment of postoperative retention of urine. In animal experimental studies, kappa-receptor agonists have an analgesic effect without urodynamic side-effects but no clinical trials on man have hitherto been undertaken. When postoperative retention of urine occurs after epidural opioid treatment, clean intermittent catheterization or introduction of a thin suprapubic catheter are recommended.
Translated title of the contribution[Urinary retention in connection with postoperative pain treatment with epidural opioids]
Original languageDanish
JournalUgeskr Laeger
Volume152
Issue number22
Pages (from-to)1574-1577
Number of pages4
Publication statusPublished - 1990

ID: 32492669