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Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017

Research output: Contribution to journalJournal articleResearchpeer-review


  • Toby O Smith
  • Michael Mansfield
  • Gillian A Hawker
  • David J Hunter
  • Lyn M March
  • Maarten Boers
  • Beverley J Shea
  • Robin Christensen
  • Francis Guillemin
  • Caroline B Terwee
  • Paula R Williamson
  • Ewa M Roos
  • Richard F Loeser
  • Thomas J Schnitzer
  • Margreet Kloppenburg
  • Tuhina Neogi
  • Christoph H Ladel
  • Gurdyal Kalsi
  • Ulrike Kaiser
  • Thomas W Buttel
  • Anne E Ashford
  • Ali Mobasheri
  • Nigel K Arden
  • Alan Tennant
  • Marc C Hochberg
  • Maarten de Wit
  • Peter Tugwell
  • Philip G Conaghan
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OBJECTIVE: To assess the uptake of the OMERACT-OARSI (Outcome Measures in Rheumatology- Osteoarthritis Research Society International) core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials.

METHODS: There were 382 trials of hip and/or knee OA identified from the registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phases.

RESULTS: COS adoption decreased from 61% between 1997 and 2001 to 38% between 2012 and 2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient's global assessment (48%) was the principal missing domain.

CONCLUSION: Limited adoption of the COS domains indicates that further consideration to improve uptake is required.

Original languageEnglish
JournalJournal of Rheumatology
Issue number8
Pages (from-to)976-980
Number of pages5
Publication statusPublished - Aug 2019

    Research areas

  • Adoption, Core outcome set, Domain, OMERACT, Trial registration

ID: 57855722