Unmet Medical Needs in Metastatic Lung and Digestive Neuroendocrine Neoplasms

Jaume Capdevila, Lisa Bodei, Philippa Davies, Vera Gorbounova, Robert T Jensen, Ulrich P Knigge, Guenter J Krejs, Eric Krenning, Juan Manuel O'Connor, Marc Peeters, Guido Rindi, Ramon Salazar, Marie-Pierre Vullierme, Marianne E Pavel, ENETS 2016 Munich Advisory Board Participants

7 Citations (Scopus)


Unmet medical needs are not infrequent in oncology, and these needs are usually of higher magnitude in rare cancers. The field of neuroendocrine neoplasms (NENs) has evolved rapidly during the last decade, and, currently, a new WHO classification is being implemented and several treatment options are available in the metastatic setting after the results of prospective phase III clinical trials. However, several questions are still unanswered, and decisions in our daily clinical practice should be made with limited evidence. In the 2016 meeting of the advisory board of the European Neuroendocrine Tumor Society (ENETS), the main unmet medical needs in the metastatic NENs setting were deeply discussed, and several proposals to try to solve them are presented in this article, including biomarkers, imaging, and therapy.

Original languageEnglish
Issue number1
Pages (from-to)18-25
Number of pages8
Publication statusPublished - 1 Jan 2019


  • Biomarkers
  • Imaging
  • Metastasis
  • Neuroendocrine neoplasms
  • Therapy
  • Unmet medical needs
  • Digestive System Neoplasms/diagnosis
  • Humans
  • Lung Neoplasms/diagnosis
  • Neuroendocrine Tumors/diagnostic imaging
  • Biomedical Research/trends
  • Drug Development
  • Biomarkers, Tumor/metabolism


Dive into the research topics of 'Unmet Medical Needs in Metastatic Lung and Digestive Neuroendocrine Neoplasms'. Together they form a unique fingerprint.

Cite this