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Ultrasound-assisted thrombolysis for acute intermediate-high-risk pulmonary embolism

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  1. Post-operative recovery is not a limiting factor for adjuvant chemotherapy in patients undergoing surgery for colorectal cancer

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  2. Providing targeted healthcare services for immigrants with complex health needs

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  3. Multivitamin intake does not affect the risk of preterm and very preterm birth

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  4. Time from injury to arrival at the trauma centre in patients undergoing interhospital transfer

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  5. Face masks for the prevention of COVID-19 - Rationale and design of the randomised controlled trial DANMASK-19

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  1. Renal 123I-MIBG Uptake before and after Live-Donor Kidney Transplantation

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  2. Coronary risk of patients with valvular heart disease: prospective validation of CT-Valve Score

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  3. Vascular function in adults with cyanotic congenital heart disease

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  4. Cognitive impairment and psychopathology in out-of-hospital cardiac arrest survivors in Denmark: The REVIVAL cohort study protocol

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  5. Fractional Flow Reserve Guided PCI in Patients With and Without Left Ventricular Hypertrophy: a DANAMI-3-PRIMULTI Sub-study

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INTRODUCTION: Eustachian tube dysfunction (ETD) may result in hearing loss, chronic otitis and cholesteatoma. With advances in treatment options, the identification of patients with obstructive ETD is becoming increasingly important. The objective of this study was to validate a Danish translation of the 7-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7).

METHODS: All participants underwent tympanometry, otomicroscopy and completed the ETDQ-7. We included 34 ears from patients with obstructive ETD who had abnormal tympanometry curves but no history of cholesteatoma or adhesive otitis. As a control group, 48 otherwise healthy ears with a normal tympanometry curve were included from patients with known sensorineural hearing loss or normal hearing.

RESULTS: A Cronbach's alpha of 0.77 indicated a good internal consistency reliability of the questionnaire. The mean ETDQ-7 score in the obstructive ETD group was 31 versus 13.5 in the control group (p = 0.00). A receiver operating characteristics analysis produced an area under the curve of 94%, showing excellent discriminatory abilities between the groups.

CONCLUSIONS: The ETDQ-7 has previously been validated in English, German, Dutch and Portuguese, demonstrating good clinical relevance. The Danish translation of the ETDQ-7 has produced similar results and may be valuable in diagnosing obstructive ETD and in monitoring the effect of balloon dilation of the Eustachian tube.

FUNDING: none. The study was approved by the Danish Data Protection Agency (VD-2018-33, I-Suite 6229).

Original languageEnglish
Article numberA00090644
JournalDanish Medical Journal
Volume67
Issue number7
ISSN1603-9629
Publication statusPublished - 1 Jul 2020

ID: 60799875