Type VI collagen turnover-related peptides-novel serological biomarkers of muscle mass and anabolic response to loading in young men

Anders Nedergaard; Shu Sun; Morten A Karsdal; Kim Steen Henriksen; Michael Kjær; Yunyun Lou; Yi He; Qinlong Zheng; Charlotte Suetta

doi:10.1007/s13539-013-0114-x

Type VI collagen turnover-related peptides-novel serological biomarkers of muscle mass and anabolic response to loading in young men

Anders Nedergaard
, Shu Sun
, Morten A Karsdal
, Kim Steen Henriksen
, Michael Kjær
, Yunyun Lou
, Yi He
, Qinlong Zheng
, Charlotte Suetta

Department of Orthopaedic Surgery

50 Citations (Scopus)

Abstract

Immobilization-induced loss of muscle mass is a complex phenomenon with several parallels to sarcopenic and cachectic muscle loss. Muscle is a large organ with a protein turnover that is orders of magnitude larger than most other tissues. Thus, we hypothesize that muscle loss and regain is reflected by peptide biomarkers derived from type VI collagen processing released in the circulation.

Original language	English
Journal	Journal of Cachexia, Sarcopenia and Muscle
Volume	4
Issue number	4
Pages (from-to)	267-75
Number of pages	9
ISSN	2190-5991
DOIs	https://doi.org/10.1007/s13539-013-0114-x
Publication status	Published - Dec 2013

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abstract = "Immobilization-induced loss of muscle mass is a complex phenomenon with several parallels to sarcopenic and cachectic muscle loss. Muscle is a large organ with a protein turnover that is orders of magnitude larger than most other tissues. Thus, we hypothesize that muscle loss and regain is reflected by peptide biomarkers derived from type VI collagen processing released in the circulation.",

author = "Anders Nedergaard and Shu Sun and Karsdal, \{Morten A\} and Henriksen, \{Kim Steen\} and Michael Kj{\ae}r and Yunyun Lou and Yi He and Qinlong Zheng and Charlotte Suetta",

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T1 - Type VI collagen turnover-related peptides-novel serological biomarkers of muscle mass and anabolic response to loading in young men

AU - Nedergaard, Anders

AU - Sun, Shu

AU - Karsdal, Morten A

AU - Henriksen, Kim Steen

AU - Kjær, Michael

AU - Lou, Yunyun

AU - He, Yi

AU - Zheng, Qinlong

AU - Suetta, Charlotte

PY - 2013/12

Y1 - 2013/12

N2 - Immobilization-induced loss of muscle mass is a complex phenomenon with several parallels to sarcopenic and cachectic muscle loss. Muscle is a large organ with a protein turnover that is orders of magnitude larger than most other tissues. Thus, we hypothesize that muscle loss and regain is reflected by peptide biomarkers derived from type VI collagen processing released in the circulation.

AB - Immobilization-induced loss of muscle mass is a complex phenomenon with several parallels to sarcopenic and cachectic muscle loss. Muscle is a large organ with a protein turnover that is orders of magnitude larger than most other tissues. Thus, we hypothesize that muscle loss and regain is reflected by peptide biomarkers derived from type VI collagen processing released in the circulation.

U2 - 10.1007/s13539-013-0114-x

DO - 10.1007/s13539-013-0114-x

M3 - Journal article

C2 - 23943593

SN - 2190-5991

VL - 4

SP - 267

EP - 275

JO - Journal of Cachexia, Sarcopenia and Muscle

JF - Journal of Cachexia, Sarcopenia and Muscle

IS - 4

ER -

Type VI collagen turnover-related peptides-novel serological biomarkers of muscle mass and anabolic response to loading in young men

Abstract

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