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Twin pregnancy possibly associated with high semen quality

    19 Citations (Scopus)

    Abstract

    BACKGROUND: Recent studies found an association between a long waiting time to pregnancy (TTP) and reduced probability of twinning and a reduced dizygotic (DZ) twinning rate in subfertile men. However, it remains unsolved whether semen quality is associated with twin offspring. We therefore studied the semen quality in a group of fathers of naturally conceived twins.

    METHODS: In this study, 37 fathers of DZ twins and 15 fathers of monozygotic (MZ) twins participated, and 349 normal fertile men served as a reference group. All men delivered a semen sample, underwent a physical examination and completed a questionnaire.

    RESULTS: After adjustment, fathers of DZ and MZ twins had 3.6 (95% CI 1.7; 5.4) and 4.6 (95% CI 2.0; 7.2) percentage points higher percentage of sperm cells with normal morphologic features and percentages of motile sperm cells were 11.5 (95% CI 7.2; 15.9) and 12.5 (95% CI 6.3; 18.6) percentage points higher than the reference group (P < 0.01). Fathers of DZ twins and MZ twins had 24.7 (95% CI; -9.1; 71.3) and 17.0% (-25.2%; 83.0%) higher sperm concentration than the reference group.

    CONCLUSIONS: Fathers of DZ twins had a better semen quality than the reference group, which supports the assumption that spontaneous DZ twinning rate can be used as a sensor of male fecundity of a population.

    Original languageEnglish
    JournalHuman Reproduction
    Volume22
    Issue number3
    Pages (from-to)751-5
    Number of pages5
    ISSN0268-1161
    DOIs
    Publication statusPublished - Mar 2007

    Keywords

    • Female
    • Fertility
    • Humans
    • Male
    • Pregnancy
    • Pregnancy, Multiple/physiology
    • Semen/physiology
    • Sperm Count
    • Sperm Motility
    • Twins
    • Twins, Dizygotic
    • Twins, Monozygotic

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