Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Triphasic Waves Are Generated by Widespread Bilateral Cortical Networks

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Diabetic Neuropathy Influences Control of Spinal Mechanisms

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Early automatic detection of Parkinson's disease based on sleep recordings

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Sleep-wake transition in narcolepsy and healthy controls using a support vector machine

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Beyond the double banana: improved recognition of temporal lobe seizures in long-term EEG

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. A computerized algorithm for arousal detection in healthy adults and patients with Parkinson disease

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Global Characterisation of Coagulopathy in Isolated Traumatic Brain Injury (iTBI): A CENTER-TBI Analysis

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Can tendon reflexes be elicited by both stretch and vibration in man?

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Understanding the relationship between cognitive performance and function in daily life after traumatic brain injury

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Mustafa Aykut Kural
  • Martin Fabricius
  • Jakob Christensen
  • Peter W Kaplan
  • Sándor Beniczky
View graph of relations

PURPOSE: Triphasic waves (TWs) have been observed in the EEG recorded in patients with various types of encephalopathy, yet their genesis and significance is still debated. The aim of this study was to elucidate the localization of the cortical generators of TWs using EEG source imaging.

METHODS: In 20 consecutive patients who had encephalopathy with TWs, EEG source imaging of the first negative and the positive phases of the TW was performed. Three different approaches were used: equivalent current dipoles, a distributed source model, and a recently described spatial filtration method for visualizing EEG in source space.

RESULTS: Equivalent current dipole models failed to provide valid solutions. The distributed source model and the spatial filtration method suggested that TWs were generated by large, bilateral cortical networks, invariably involving the anterior frontal and the temporo-polar areas.

CONCLUSIONS: Source imaging localized TWs to anterior frontal and temporo-frontal structures. Involvement of these regions is consistent with the typical pathophysiological changes of altered consciousness and cognitive changes observed in patients with TW encephalopathy.

Original languageEnglish
JournalJournal of clinical neurophysiology : official publication of the American Electroencephalographic Society
Volume38
Issue number5
Pages (from-to)415-419
Number of pages5
ISSN0736-0258
DOIs
Publication statusPublished - 1 Sep 2021

    Research areas

  • Brain Diseases, Electroencephalography, Humans

ID: 61991761