Treatment of severe drooling with botulinum toxin in amyotrophic lateral sclerosis and Parkinson's disease: efficacy and possible mechanisms

Eigild Møller; Merete Karlsborg; Allan Bardow; Joan Lykkeaa; Flemming H Nissen; Merete Bakke

doi:10.3109/00016357.2010.545035

Treatment of severe drooling with botulinum toxin in amyotrophic lateral sclerosis and Parkinson's disease: efficacy and possible mechanisms

Eigild Møller, Merete Karlsborg, Allan Bardow, Joan Lykkeaa, Flemming H Nissen, Merete Bakke

23 Citations (Scopus)

Abstract

Drooling in neurodegenerative diseases is associated with social impediment. Previous treatments of drooling have little effect or are effective but with severe side effects. Therefore, there is a need to test new methods such as the use of botulinum toxin type A (BTX-A).

Original language	English
Journal	Acta Odontologica Scandinavica
Volume	69
Issue number	3
Pages (from-to)	151-7
Number of pages	7
ISSN	0001-6357
DOIs	https://doi.org/10.3109/00016357.2010.545035
Publication status	Published - 2011

Keywords

Acetylcholine
Aged
Algorithms
Amyotrophic Lateral Sclerosis
Botulinum Toxins, Type A
Female
Humans
Injections
Male
Neuromuscular Agents
Parkinson Disease
Parotid Gland
Prospective Studies
Saliva
Salivation
Secretory Rate
Sialorrhea
Submandibular Gland
Ultrasonography, Interventional

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title = "Treatment of severe drooling with botulinum toxin in amyotrophic lateral sclerosis and Parkinson's disease: efficacy and possible mechanisms",

abstract = "Drooling in neurodegenerative diseases is associated with social impediment. Previous treatments of drooling have little effect or are effective but with severe side effects. Therefore, there is a need to test new methods such as the use of botulinum toxin type A (BTX-A).",

keywords = "Acetylcholine, Aged, Algorithms, Amyotrophic Lateral Sclerosis, Botulinum Toxins, Type A, Female, Humans, Injections, Male, Neuromuscular Agents, Parkinson Disease, Parotid Gland, Prospective Studies, Saliva, Salivation, Secretory Rate, Sialorrhea, Submandibular Gland, Ultrasonography, Interventional",

author = "Eigild M{\o}ller and Merete Karlsborg and Allan Bardow and Joan Lykkeaa and Nissen, {Flemming H} and Merete Bakke",

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language = "English",

volume = "69",

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T1 - Treatment of severe drooling with botulinum toxin in amyotrophic lateral sclerosis and Parkinson's disease

T2 - efficacy and possible mechanisms

AU - Møller, Eigild

AU - Karlsborg, Merete

AU - Bardow, Allan

AU - Lykkeaa, Joan

AU - Nissen, Flemming H

AU - Bakke, Merete

PY - 2011

Y1 - 2011

N2 - Drooling in neurodegenerative diseases is associated with social impediment. Previous treatments of drooling have little effect or are effective but with severe side effects. Therefore, there is a need to test new methods such as the use of botulinum toxin type A (BTX-A).

AB - Drooling in neurodegenerative diseases is associated with social impediment. Previous treatments of drooling have little effect or are effective but with severe side effects. Therefore, there is a need to test new methods such as the use of botulinum toxin type A (BTX-A).

KW - Acetylcholine

KW - Aged

KW - Algorithms

KW - Amyotrophic Lateral Sclerosis

KW - Botulinum Toxins, Type A

KW - Female

KW - Humans

KW - Injections

KW - Male

KW - Neuromuscular Agents

KW - Parkinson Disease

KW - Parotid Gland

KW - Prospective Studies

KW - Saliva

KW - Salivation

KW - Secretory Rate

KW - Sialorrhea

KW - Submandibular Gland

KW - Ultrasonography, Interventional

U2 - 10.3109/00016357.2010.545035

DO - 10.3109/00016357.2010.545035

M3 - Journal article

C2 - 21198339

SN - 0001-6357

VL - 69

SP - 151

EP - 157

JO - Acta Odontologica Scandinavica

JF - Acta Odontologica Scandinavica

IS - 3

ER -

Treatment of severe drooling with botulinum toxin in amyotrophic lateral sclerosis and Parkinson's disease: efficacy and possible mechanisms

Abstract

Keywords

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