Tranexamic acid for upper gastrointestinal bleeding

Lise Lotte Gluud; Sarah Louise Klingenberg; Ebbe Langholz

doi:10.1002/14651858.CD006640.pub2

Tranexamic acid for upper gastrointestinal bleeding

Lise Lotte Gluud, Sarah Louise Klingenberg, Ebbe Langholz

Copenhagen Trial Unit

72 Citations (Scopus)

Abstract

Tranexamic acid reduces haemorrhage through its antifibrinolytic effects. In a previous version of the present review, we found that tranexamic acid may reduce mortality. The present review includes updated searches of randomised trials on tranexamic acid versus placebo, cimetidine or lansoprazole.

Original language	English
Journal	Cochrane Database of Systematic Reviews
Volume	1
Pages (from-to)	CD006640
ISSN	1469-493X
DOIs	https://doi.org/10.1002/14651858.CD006640.pub2
Publication status	Published - 2012

Keywords

2-Pyridinylmethylsulfinylbenzimidazoles
Administration, Oral
Aluminum Hydroxide
Anti-Ulcer Agents
Antifibrinolytic Agents
Cimetidine
Drug Combinations
Endoscopy, Gastrointestinal
Gastrointestinal Hemorrhage
Humans
Injections, Intravenous
Magnesium
Magnesium Hydroxide
Randomized Controlled Trials as Topic
Tranexamic Acid

Access to Document

10.1002/14651858.CD006640.pub2

Cite this

@article{90fa84d59b5140afaca7dc99bd3484c8,

title = "Tranexamic acid for upper gastrointestinal bleeding",

abstract = "Tranexamic acid reduces haemorrhage through its antifibrinolytic effects. In a previous version of the present review, we found that tranexamic acid may reduce mortality. The present review includes updated searches of randomised trials on tranexamic acid versus placebo, cimetidine or lansoprazole.",

keywords = "2-Pyridinylmethylsulfinylbenzimidazoles, Administration, Oral, Aluminum Hydroxide, Anti-Ulcer Agents, Antifibrinolytic Agents, Cimetidine, Drug Combinations, Endoscopy, Gastrointestinal, Gastrointestinal Hemorrhage, Humans, Injections, Intravenous, Magnesium, Magnesium Hydroxide, Randomized Controlled Trials as Topic, Tranexamic Acid",

author = "Gluud, {Lise Lotte} and Klingenberg, {Sarah Louise} and Ebbe Langholz",

year = "2012",

doi = "10.1002/14651858.CD006640.pub2",

language = "English",

volume = "1",

pages = "CD006640",

journal = "Cochrane Database of Systematic Reviews",

issn = "1469-493X",

publisher = "Update Software Ltd",

}

TY - JOUR

T1 - Tranexamic acid for upper gastrointestinal bleeding

AU - Gluud, Lise Lotte

AU - Klingenberg, Sarah Louise

AU - Langholz, Ebbe

PY - 2012

Y1 - 2012

N2 - Tranexamic acid reduces haemorrhage through its antifibrinolytic effects. In a previous version of the present review, we found that tranexamic acid may reduce mortality. The present review includes updated searches of randomised trials on tranexamic acid versus placebo, cimetidine or lansoprazole.

AB - Tranexamic acid reduces haemorrhage through its antifibrinolytic effects. In a previous version of the present review, we found that tranexamic acid may reduce mortality. The present review includes updated searches of randomised trials on tranexamic acid versus placebo, cimetidine or lansoprazole.

KW - 2-Pyridinylmethylsulfinylbenzimidazoles

KW - Administration, Oral

KW - Aluminum Hydroxide

KW - Anti-Ulcer Agents

KW - Antifibrinolytic Agents

KW - Cimetidine

KW - Drug Combinations

KW - Endoscopy, Gastrointestinal

KW - Gastrointestinal Hemorrhage

KW - Humans

KW - Injections, Intravenous

KW - Magnesium

KW - Magnesium Hydroxide

KW - Randomized Controlled Trials as Topic

KW - Tranexamic Acid

U2 - 10.1002/14651858.CD006640.pub2

DO - 10.1002/14651858.CD006640.pub2

M3 - Journal article

C2 - 22258969

SN - 1469-493X

VL - 1

SP - CD006640

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

ER -

Tranexamic acid for upper gastrointestinal bleeding

Abstract

Keywords

Access to Document

Fingerprint

Cite this