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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Topological principles and developmental algorithms might refine diffusion tractography

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  1. Ex vivo diffusion-weighted MRI tractography of the Göttingen minipig limbic system

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Brain resting-state connectivity in the development of secondary hyperalgesia in healthy men

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  3. The number of neurons in specific amygdala regions is associated with boldness in mink: a study in animal personality

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  1. On the cortical connectivity in the macaque brain: a comparison of diffusion tractography and histological tracing data

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Functional and Structural Plasticity Co-express in a Left Premotor Region During Early Bimanual Skill Learning

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  3. Streamline tractography for 3D mapping of axon bundle organization in one MRI voxel using ultra-high resolution synchrotron radiation imaging

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

  4. The impact of axon orientation dispersion and 3D diameter variations on the transverse apparent diffusion coefficient

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

  • Giorgio M Innocenti
  • Tim B Dyrby
  • Gabriel Girard
  • Etienne St-Onge
  • Jean-Philippe Thiran
  • Alessandro Daducci
  • Maxime Descoteaux
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The identification and reconstruction of axonal pathways in the living brain or "ex-vivo" is promising a revolution in connectivity studies bridging the gap from animal to human neuroanatomy with extensions to brain structural-functional correlates. Unfortunately, the methods suffer from juvenile drawbacks. In this perspective paper we mention several computational and developmental principles, which might stimulate a new generation of algorithms and a discussion bridging the neuroimaging and neuroanatomy communities.

Original languageEnglish
JournalBrain structure & function
Volume224
Issue number1
Pages (from-to)1-8
Number of pages8
ISSN0177-5154
DOIs
Publication statusPublished - Jan 2019

    Research areas

  • Axons, Brain development, Brain pathways, Diffusion MRI, Tractography, Predictive Value of Tests, Brain Mapping/methods, Humans, Neural Pathways/diagnostic imaging, Neurogenesis, Brain/diagnostic imaging, Algorithms, Animals, Neuroimaging/methods, Axons/physiology, Image Interpretation, Computer-Assisted/methods, Models, Neurological, Diffusion Tensor Imaging/methods

ID: 55375742