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The Capital Region of Denmark - a part of Copenhagen University Hospital

Time trends in incidence and prevalence of chronic pancreatitis: A 25-year population-based nationwide study

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Background: Updated population-based estimates on incidence and prevalence of chronic pancreatitis are scarce. Methods: We used nationwide healthcare registries to identify all Danish patients diagnosed with chronic pancreatitis and computed crude and standardised incidence rates and prevalence estimates in 1994–2018. Incidence and prevalence were evaluated in relation to patients age and gender, aetiology (alcoholic vs. non-alcoholic) and smoking and alcohol consumption in the general Danish population. Results: The mean incidence rate of chronic pancreatitis during the study period was 12.6 per 100,000 person years for the total population, for women it was 8.6 per 100,000 person years and for men it was 16.7 per 100,000 person years. The standardised incidence rate was stable from 1994 to 2018, remaining at 12.5 per 100,000 person years in the last observation period (2014–2018). The point prevalence of chronic pancreatitis in 2016 was 153.9 per 100,000 persons. A gradual increase in standardised prevalence estimates was observed during the study period from 126.6 in 1996 to 153.9 in 2016. The mean age at chronic pancreatitis diagnosis increased from 52.1 to 60.0 years during the study period. Conclusion: The prevalence of chronic pancreatitis is increasing in the Danish population despite a stable incidence level. Improved management strategies and changes in the underlying patient population may explain these observations.

Original languageEnglish
Article number2050640620966513
JournalUnited European Gastroenterology Journal
Issue number1
Pages (from-to)82-90
Number of pages9
Publication statusPublished - Feb 2021

    Research areas

  • alcohol, Chronic pancreatitis, epidemiology, incidence, prevalence, smoking

ID: 61228407