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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Three-dimensional reconstruction of entire vertebral bodies

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Parallel plate model for trabecular bone exhibits volume fraction-dependent bias

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Constitutive relationships of fabric, density, and elastic properties in cancellous bone architecture

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Connectivity and the elastic properties of cancellous bone

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Three-dimensional methods for quantification of cancellous bone architecture

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  1. Outcomes after ORIF of Bicondylar Schatzker VI (AO type C) Tibial Plateau Fractures in an Elderly Population

    Research output: Contribution to journalJournal articleResearchpeer-review

  • A Odgaard
  • K Andersen
  • R Ullerup
  • L H Frich
  • F Melsen
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This paper describes a technique for 3-D reconstruction of large cancellous bone regions. The output is a 3-D array describing the original cancellous bone region, and the output can be used for any kind of measurement of the bone architecture. The technique was developed as a tool for researchers conducting experimental and clinical studies related to cancellous bone architecture and, ultimately, to cancellous bone quality. A set of new and unbiased methods for quantification of cancellous bone has been a stimulus for the development of the technique, as the quantification methods rely on 3-D information. The technique is based on automated serial sectioning, and all steps from specimen preparation to image segmentation are described in detail. Examples of 3-D reconstructed vertebral bodies are given. By use of the described technique, between 300 and 600 sections can be made and registered per hour, which means that an average vertebral body can be reconstructed in about 2 h. Compared to previous implementations of the general principle of serial sectioning, this is a significant improvement both in resolution and in time efficiency.

Original languageEnglish
JournalBone
Volume15
Issue number3
Pages (from-to)335-42
Number of pages8
ISSN8756-3282
DOIs
Publication statusPublished - 1 May 1994
Externally publishedYes

    Research areas

  • Aged, Humans, Image Processing, Computer-Assisted, Male, Mathematics, Spine/anatomy & histology

ID: 78746218