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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Thin or early melanoma, risk factors and associated mortality

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INTRODUCTION: The incidence of thin and early-stage melanoma is increasing in many populations, but the clinical significance of these lesions remains partly unknown.

METHODS: Firstly, melanoma deaths in Denmark (2009-2018) were followed back to establish melanoma debut in these persons. Secondly, using national registries of cancer incidence and mortality, 27,036 persons with thin or early-stage melanoma were followed-up for melanoma death.

RESULTS: It is estimated that in 11% of the persons who died from melanoma, the debut was a thin or early-stage melanoma. On follow-up of persons with thin or early-stage melanoma, the 20-year risk of dying from melanoma was 3%.

CONCLUSION: The absolute risk of melanoma death after a diagnosis with thin or early-stage melanoma is low. A subgroup of patients who are at a high risk may possibly be identified by a combination of stage, thickness, ulceration and dermal mitoses.

FUNDING: none.

TRIAL REGISTRATION: not relevant.

Original languageEnglish
Article numberA01220020
JournalDanish Medical Journal
Volume69
Issue number9
ISSN1603-9629
Publication statusPublished - 9 Aug 2022

Bibliographical note

Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

    Research areas

  • Humans, Incidence, Melanoma, Registries, Risk Factors, Skin Neoplasms/pathology

ID: 84547125