Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa

Astrid-Helene Ravn Jørgensen; Yiqiu Yao; Simon Francis Thomsen

doi:10.1155/2018/8685136

Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa

Astrid-Helene Ravn Jørgensen, Yiqiu Yao, Simon Francis Thomsen

Department of Dermatology

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).

Original language	English
Journal	Case Reports in Dermatological Medicine
Volume	2018
Pages (from-to)	8685136
ISSN	2090-6463
DOIs	https://doi.org/10.1155/2018/8685136
Publication status	Published - 2018

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abstract = "Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).",

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AU - Thomsen, Simon Francis

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N2 - Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).

AB - Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).

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DO - 10.1155/2018/8685136

M3 - Journal article

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SN - 2090-6463

VL - 2018

SP - 8685136

JO - Case Reports in Dermatological Medicine

JF - Case Reports in Dermatological Medicine

ER -

Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa

Abstract

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