Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Therapeutic drug monitoring of β-lactam antibiotics

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Isoniazidinduceret toksisk hepatitis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Epidemiologi, klinik og behandling af SARS-CoV-2 infektion hos børn

    Research output: Contribution to journalReviewResearchpeer-review

  3. Det danske screeningsprogram for hæmoglobinopatier

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Udredning og behandling af mandlig infertilitet

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Malignant pertussis in a three-week-old girl

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. The effect of migration on the incidence and mortality of bloodstream infection: a Danish register-based cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Epidemiologi, klinik og behandling af SARS-CoV-2 infektion hos børn

    Research output: Contribution to journalReviewResearchpeer-review

  3. Increased short- and long-term mortality following infections in dementia: a nationwide registry-based cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Traditional β-lactam antibiotic dosing does not consider physiological changes in medical conditions such as sepsis. Optimal antibiotic exposure could be achieved by therapeutic drug monitoring (TDM). This review gives a brief summary. Current studies are sparse, but suggestive of a potential beneficial role of TDM to patients with reduced renal function, obese patients and the critically ill. TDM can potentially reduce adverse effects and optimise antibiotic exposure. However, standardised TDM methods are lacking and randomised clinical studies are warranted in order to prove clinical benefit.

Translated title of the contributionTherapeutic drug monitoring of β-lactam antibiotics
Original languageDanish
JournalUgeskrift for Laeger
Volume182
Issue number39
ISSN0041-5782
Publication statusPublished - 21 Sep 2020

ID: 61603206