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The Capital Region of Denmark - a part of Copenhagen University Hospital
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The usefulness of ultrasound colour-Doppler twinkling artefact for detecting urolithiasis compared with low dose nonenhanced computerized tomography

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This prospective study evaluates the usefulness of the twinkling artefact (TA) seen on colour-Doppler ultrasound (US) in diagnosing urolithiasis. US and standard computed tomography (CT) were performed blinded on 105 patients. B-mode US and colour-Doppler used separately and in combination showed 55% sensitivity and 99% specificity (positive predictive value [PPV] 67% and negative predictive value [NPV] 98%). Of CT verified stones, 61% were ≤3 mm. TAs were present in 74% of the B-mode stones (43% of all CT verified stones). Patients with CT verified stone disease had significantly more TAs in other foci than the stone(s) found on CT, suggestive of microlithiasis. In conclusion, colour-Doppler TA is a helpful supplement for detecting urolithiasis when CT is contraindicated. In addition, US can be valuable in monitoring stones left to pass without intervention if they have presented a TA. CT, US and US with colour-Doppler TA can be useful as complementary techniques for detecting stones.
Original languageEnglish
JournalUltrasound in Medicine & Biology
Volume38
Issue number7
Pages (from-to)1180-7
Number of pages8
ISSN0301-5629
DOIs
Publication statusPublished - 2012

    Research areas

  • Adult, Aged, Aged, 80 and over, Artifacts, Contrast Media, Female, Humans, Male, Middle Aged, Radiation Dosage, Reproducibility of Results, Sensitivity and Specificity, Tomography, X-Ray Computed, Ultrasonography, Doppler, Color, Urolithiasis

ID: 36766122