The triglyceride content in skeletal muscle is associated with hepatic but not peripheral insulin resistance in elderly twins

L G Grunnet; Esa Laurila; Ola Hansson; Peter Almgren; Leif Groop; Charlotte Brøns; Pernille Hartveit Poulsen; Allan Vaag

doi:10.1210/jc.2012-2061

The triglyceride content in skeletal muscle is associated with hepatic but not peripheral insulin resistance in elderly twins

L G Grunnet, Esa Laurila, Ola Hansson, Peter Almgren, Leif Groop, Charlotte Brøns, Pernille Hartveit Poulsen, Allan Vaag

11 Citations (Scopus)

Abstract

Total muscle triglyceride (MT) content has been associated with insulin resistance. We investigated the predictors and impact of MT on relevant metabolic parameters including peripheral and hepatic insulin resistance in elderly twins.

Original language	English
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	97
Issue number	12
Pages (from-to)	4571-7
Number of pages	7
ISSN	0021-972X
DOIs	https://doi.org/10.1210/jc.2012-2061
Publication status	Published - 2012

Keywords

Aged
Diabetes Mellitus, Type 2
Female
Glucose Intolerance
Humans
Insulin
Insulin Resistance
Liver
Male
Middle Aged
Muscle, Skeletal
Quantitative Trait, Heritable
Registries
Triglycerides
Twins

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10.1210/jc.2012-2061

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title = "The triglyceride content in skeletal muscle is associated with hepatic but not peripheral insulin resistance in elderly twins",

abstract = "Total muscle triglyceride (MT) content has been associated with insulin resistance. We investigated the predictors and impact of MT on relevant metabolic parameters including peripheral and hepatic insulin resistance in elderly twins.",

keywords = "Aged, Diabetes Mellitus, Type 2, Female, Glucose Intolerance, Humans, Insulin, Insulin Resistance, Liver, Male, Middle Aged, Muscle, Skeletal, Quantitative Trait, Heritable, Registries, Triglycerides, Twins",

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AU - Grunnet, L G

AU - Laurila, Esa

AU - Hansson, Ola

AU - Almgren, Peter

AU - Groop, Leif

AU - Brøns, Charlotte

AU - Poulsen, Pernille Hartveit

AU - Vaag, Allan

PY - 2012

Y1 - 2012

N2 - Total muscle triglyceride (MT) content has been associated with insulin resistance. We investigated the predictors and impact of MT on relevant metabolic parameters including peripheral and hepatic insulin resistance in elderly twins.

AB - Total muscle triglyceride (MT) content has been associated with insulin resistance. We investigated the predictors and impact of MT on relevant metabolic parameters including peripheral and hepatic insulin resistance in elderly twins.

KW - Aged

KW - Diabetes Mellitus, Type 2

KW - Female

KW - Glucose Intolerance

KW - Humans

KW - Insulin

KW - Insulin Resistance

KW - Liver

KW - Male

KW - Middle Aged

KW - Muscle, Skeletal

KW - Quantitative Trait, Heritable

KW - Registries

KW - Triglycerides

KW - Twins

U2 - 10.1210/jc.2012-2061

DO - 10.1210/jc.2012-2061

M3 - Journal article

C2 - 23055544

VL - 97

SP - 4571

EP - 4577

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

SN - 0021-972X

IS - 12

ER -

The triglyceride content in skeletal muscle is associated with hepatic but not peripheral insulin resistance in elderly twins

Abstract

Keywords

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