TY - JOUR
T1 - The Surgical Management of Lung Neuroendocrine Neoplasms
AU - Soldath, Patrick
AU - Petersen, René Horsleben
PY - 2023/3/9
Y1 - 2023/3/9
N2 - This review summarizes key recent developments relevant to the surgical management of lung neuroendocrine neoplasms (L-NENs), including typical and atypical carcinoids, large cell neuroendocrine carcinoma, and small cell lung carcinoma. This review includes recent insights into the classification, clinical presentation, diagnostic workup, treatment options, and follow-up. Highlighted topics include general principles of surgery in localized or locally advanced or metastatic L-NENs, lung-sparing surgery for small, peripheral typical carcinoids, adjuvant and systemic therapies for typical and atypical carcinoids, and surgery and adjuvant therapies for large cell neuroendocrine carcinoma and small cell lung carcinoma.
AB - This review summarizes key recent developments relevant to the surgical management of lung neuroendocrine neoplasms (L-NENs), including typical and atypical carcinoids, large cell neuroendocrine carcinoma, and small cell lung carcinoma. This review includes recent insights into the classification, clinical presentation, diagnostic workup, treatment options, and follow-up. Highlighted topics include general principles of surgery in localized or locally advanced or metastatic L-NENs, lung-sparing surgery for small, peripheral typical carcinoids, adjuvant and systemic therapies for typical and atypical carcinoids, and surgery and adjuvant therapies for large cell neuroendocrine carcinoma and small cell lung carcinoma.
UR - http://www.scopus.com/inward/record.url?scp=85151455026&partnerID=8YFLogxK
U2 - 10.3390/cancers15061695
DO - 10.3390/cancers15061695
M3 - Review
C2 - 36980581
SN - 2072-6694
VL - 15
JO - Cancers
JF - Cancers
IS - 6
M1 - 1695
ER -