Harvard
Tong, D, Constantinidou, A, Engelmann, B, Chamberlain, F, Thway, K, Fisher, C, Hayes, A, Fotiadis, N, Messiou, C, Miah, AB, Zaidi, SH, Benson, C, VAN DER Graaf, W & Jones, RL 2019, '
The Role of Local Therapy in Multi-focal Epithelioid Haemangioendothelioma'
Anticancer Research, vol. 39, no. 9, pp. 4891-4896.
https://doi.org/10.21873/anticanres.13675
APA
Tong, D., Constantinidou, A., Engelmann, B., Chamberlain, F., Thway, K., Fisher, C., ... Jones, R. L. (2019).
The Role of Local Therapy in Multi-focal Epithelioid Haemangioendothelioma.
Anticancer Research,
39(9), 4891-4896.
https://doi.org/10.21873/anticanres.13675
CBE
Tong D, Constantinidou A, Engelmann B, Chamberlain F, Thway K, Fisher C, Hayes A, Fotiadis N, Messiou C, Miah AB, Zaidi SH, Benson C, VAN DER Graaf W, Jones RL. 2019.
The Role of Local Therapy in Multi-focal Epithelioid Haemangioendothelioma.
Anticancer Research. 39(9):4891-4896.
https://doi.org/10.21873/anticanres.13675
MLA
Vancouver
Author
Tong, Daniel ; Constantinidou, Anastasia ; Engelmann, Bodil ; Chamberlain, Florence ; Thway, Khin ; Fisher, Cyril ; Hayes, Andrew ; Fotiadis, Nicos ; Messiou, Christina ; Miah, Aisha B ; Zaidi, Shane H ; Benson, Charlotte ; VAN DER Graaf, Winette ; Jones, Robin L. /
The Role of Local Therapy in Multi-focal Epithelioid Haemangioendothelioma. In:
Anticancer Research. 2019 ; Vol. 39, No. 9. pp. 4891-4896.
Bibtex
@article{c0fcbe5d5e294d17a5b56126ed806e9d,
title = "The Role of Local Therapy in Multi-focal Epithelioid Haemangioendothelioma",
abstract = "BACKGROUND/AIM: Epithelioid haemangioendothelioma (EHE) is a rare tumor with a wide spectrum of clinical behavior. There is no consensus on the role of local therapy in symptomatic, multi-focal disease.PATIENTS AND METHODS: A retrospective review of patients presenting to the Royal Marsden Hospital between January 2000 and December 2017 was conducted.RESULTS: Fifty-three patients with EHE were identified, of which 18 patients (34.0{\%}) received local therapy, and 11 patients (20.8{\%}) underwent active surveillance. A variety of local treatment modalities were used with few toxicities, and local recurrence was managed with other local treatments or systemic therapy. Distal disease progression was infrequent (n=4, 7.5{\%}). Patients who developed pleural effusion (n=5, 9.4{\%}) had poor outcome irrespective of treatment.CONCLUSION: Local therapy has a role in a selected patient group managed in a multidisciplinary setting, including patients with indolent disease, and patients with a solitary area of progression/symptomatic disease.",
keywords = "Adolescent, Adult, Aged, Combined Modality Therapy, Disease Management, Female, Hemangioendothelioma, Epithelioid/mortality, Humans, Male, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Pleural Effusion/pathology, Prognosis, Watchful Waiting, Young Adult",
author = "Daniel Tong and Anastasia Constantinidou and Bodil Engelmann and Florence Chamberlain and Khin Thway and Cyril Fisher and Andrew Hayes and Nicos Fotiadis and Christina Messiou and Miah, {Aisha B} and Zaidi, {Shane H} and Charlotte Benson and {VAN DER Graaf}, Winette and Jones, {Robin L}",
note = "Copyright{\circledC} 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.",
year = "2019",
month = "9",
doi = "10.21873/anticanres.13675",
language = "English",
volume = "39",
pages = "4891--4896",
journal = "Anticancer Research",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "9",
}
RIS
TY - JOUR
T1 - The Role of Local Therapy in Multi-focal Epithelioid Haemangioendothelioma
AU - Tong, Daniel
AU - Constantinidou, Anastasia
AU - Engelmann, Bodil
AU - Chamberlain, Florence
AU - Thway, Khin
AU - Fisher, Cyril
AU - Hayes, Andrew
AU - Fotiadis, Nicos
AU - Messiou, Christina
AU - Miah, Aisha B
AU - Zaidi, Shane H
AU - Benson, Charlotte
AU - VAN DER Graaf, Winette
AU - Jones, Robin L
N1 - Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
PY - 2019/9
Y1 - 2019/9
N2 - BACKGROUND/AIM: Epithelioid haemangioendothelioma (EHE) is a rare tumor with a wide spectrum of clinical behavior. There is no consensus on the role of local therapy in symptomatic, multi-focal disease.PATIENTS AND METHODS: A retrospective review of patients presenting to the Royal Marsden Hospital between January 2000 and December 2017 was conducted.RESULTS: Fifty-three patients with EHE were identified, of which 18 patients (34.0%) received local therapy, and 11 patients (20.8%) underwent active surveillance. A variety of local treatment modalities were used with few toxicities, and local recurrence was managed with other local treatments or systemic therapy. Distal disease progression was infrequent (n=4, 7.5%). Patients who developed pleural effusion (n=5, 9.4%) had poor outcome irrespective of treatment.CONCLUSION: Local therapy has a role in a selected patient group managed in a multidisciplinary setting, including patients with indolent disease, and patients with a solitary area of progression/symptomatic disease.
AB - BACKGROUND/AIM: Epithelioid haemangioendothelioma (EHE) is a rare tumor with a wide spectrum of clinical behavior. There is no consensus on the role of local therapy in symptomatic, multi-focal disease.PATIENTS AND METHODS: A retrospective review of patients presenting to the Royal Marsden Hospital between January 2000 and December 2017 was conducted.RESULTS: Fifty-three patients with EHE were identified, of which 18 patients (34.0%) received local therapy, and 11 patients (20.8%) underwent active surveillance. A variety of local treatment modalities were used with few toxicities, and local recurrence was managed with other local treatments or systemic therapy. Distal disease progression was infrequent (n=4, 7.5%). Patients who developed pleural effusion (n=5, 9.4%) had poor outcome irrespective of treatment.CONCLUSION: Local therapy has a role in a selected patient group managed in a multidisciplinary setting, including patients with indolent disease, and patients with a solitary area of progression/symptomatic disease.
KW - Adolescent
KW - Adult
KW - Aged
KW - Combined Modality Therapy
KW - Disease Management
KW - Female
KW - Hemangioendothelioma, Epithelioid/mortality
KW - Humans
KW - Male
KW - Middle Aged
KW - Neoplasm Recurrence, Local
KW - Neoplasm Staging
KW - Pleural Effusion/pathology
KW - Prognosis
KW - Watchful Waiting
KW - Young Adult
U2 - 10.21873/anticanres.13675
DO - 10.21873/anticanres.13675
M3 - Journal article
VL - 39
SP - 4891
EP - 4896
JO - Anticancer Research
JF - Anticancer Research
SN - 0250-7005
IS - 9
ER -