The role of leptin in human lipid and glucose metabolism: the effects of acute recombinant human leptin infusion in young healthy males

Emil Wolsk; Helene Mygind; Thomas S Grøndahl; Bente K Pedersen; Gerrit van Hall

doi:10.3945/ajcn.111.012260

The role of leptin in human lipid and glucose metabolism: the effects of acute recombinant human leptin infusion in young healthy males

Emil Wolsk, Helene Mygind, Thomas S Grøndahl, Bente K Pedersen, Gerrit van Hall

22 Citations (Scopus)

Abstract

Obese and lean humans treated with leptin have not experienced convincing weight-loss results compared with the dramatic weight losses observed in obese rodents.

Original language	English
Journal	American Journal of Clinical Nutrition
Volume	94
Issue number	6
Pages (from-to)	1533-44
Number of pages	12
ISSN	0002-9165
DOIs	https://doi.org/10.3945/ajcn.111.012260
Publication status	Published - 2011

Keywords

AMP-Activated Protein Kinases
Adipose Tissue
Adult
Glucose
Humans
Leptin
Lipid Metabolism
Lipid Peroxidation
Male
Muscle, Skeletal
Obesity
Oxidation-Reduction
Palmitic Acid
Recombinant Proteins
Reference Values
Signal Transduction
Young Adult

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10.3945/ajcn.111.012260

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title = "The role of leptin in human lipid and glucose metabolism: the effects of acute recombinant human leptin infusion in young healthy males",

abstract = "Obese and lean humans treated with leptin have not experienced convincing weight-loss results compared with the dramatic weight losses observed in obese rodents.",

keywords = "AMP-Activated Protein Kinases, Adipose Tissue, Adult, Glucose, Humans, Leptin, Lipid Metabolism, Lipid Peroxidation, Male, Muscle, Skeletal, Obesity, Oxidation-Reduction, Palmitic Acid, Recombinant Proteins, Reference Values, Signal Transduction, Young Adult",

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AU - Wolsk, Emil

AU - Mygind, Helene

AU - Grøndahl, Thomas S

AU - Pedersen, Bente K

AU - van Hall, Gerrit

PY - 2011

Y1 - 2011

N2 - Obese and lean humans treated with leptin have not experienced convincing weight-loss results compared with the dramatic weight losses observed in obese rodents.

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KW - AMP-Activated Protein Kinases

KW - Adipose Tissue

KW - Adult

KW - Glucose

KW - Humans

KW - Leptin

KW - Lipid Metabolism

KW - Lipid Peroxidation

KW - Male

KW - Muscle, Skeletal

KW - Obesity

KW - Oxidation-Reduction

KW - Palmitic Acid

KW - Recombinant Proteins

KW - Reference Values

KW - Signal Transduction

KW - Young Adult

U2 - 10.3945/ajcn.111.012260

DO - 10.3945/ajcn.111.012260

M3 - Journal article

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SN - 0002-9165

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EP - 1544

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

IS - 6

ER -

The role of leptin in human lipid and glucose metabolism: the effects of acute recombinant human leptin infusion in young healthy males

Abstract

Keywords

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