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The Capital Region of Denmark - a part of Copenhagen University Hospital
E-pub ahead of print

The relation of basic self-disturbance to self-harm, eating disorder symptomatology and other clinical features: Exploration in an early psychosis sample

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  1. Concordance of child self-reported psychotic experiences with interview- and observer-based psychotic experiences

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Development of a fidelity scale for Danish specialized early interventions service

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Anomalies of imagination in the schizophrenia-spectrum: Empirical findings

    Research output: Contribution to journalComment/debateResearchpeer-review

  2. EAFI: Examination of Anomalous Fantasy and Imagination

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  • Andreas R Rasmussen
  • Daniel Reich
  • Suzie Lavoie
  • Emily Li
  • Jessica A Hartmann
  • Meredith McHugh
  • Thomas J Whitford
  • Barnaby Nelson
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BACKGROUND AND AIMS: The notion of basic self-disturbance has been proposed as a core feature of schizophrenia-spectrum disorders and as an indicator of future transition to psychosis in high-risk populations. However, the relation of this notion to many clinical characteristics has not been explored. The aim of this study was: (a) to investigate the distribution of self-disturbance and other symptoms dimensions in ultra-high risk (UHR), first-episode psychosis (FEP) and healthy control groups; and (b) to explore the association of self-disturbance with a history of self-harm, suicidal attempt, eating disorder symptomatology, school bullying victimization and sexual or physical abuse.

METHODS: Patients with UHR status (n = 38) or FEP (n = 26) and healthy controls (n = 33) were assessed with the Examination of Anomalous Self-Experience (EASE) and the Comprehensive Assessment of at Risk Mental States (CAARMS). The clinical-historical variables were assessed through medical records.

RESULTS: The FEP group scored significantly higher on the EASE than the UHR group, which scored significantly higher than the healthy control group, which had a very low score. Multivariate logistic regression analyses revealed that higher EASE score was significantly associated with a history of self-harm, disordered eating and bullying victimization (but not with suicide attempts or sexual/physical abuse) after controlling for positive, negative and depressive symptoms.

CONCLUSION: These novel findings suggest that self-disturbance may be related to a history of school bullying victimization, self-harm and eating disorder symptomatology in patients with or at-risk of psychosis. If further confirmed, these findings are potentially relevant to clinical risk assessment and therapy.

Original languageEnglish
JournalEarly Intervention in Psychiatry
ISSN1751-7885
DOIs
Publication statusE-pub ahead of print - 2 Jul 2019

ID: 58960656