Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Cozzi-Lepri, A ; Paredes ; Phillips, A N ; Clotet, B ; Kjaer, J ; Von Wyl, V ; Kronborg, Gitte ; Castagna, A ; Bogner, J R ; Lundgren, Jens Dilling ; EuroSIDA in EuroCoord. / The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*. In: HIV Medicine. 2012 ; Vol. 13, No. 1. pp. 62-72.

Bibtex

@article{ac0634f232364b43b70cdaf75d0ac682,
title = "The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*",
abstract = "Virological failure of first-generation nonnucleoside reverse transcriptase inhibitors (NNRTIs) can compromise the efficacy of etravirine as a result of the accumulation of NNRTI resistance mutations. How quickly NNRTI resistance accumulates in patients with a delayed switch from nevirapine or efavirenz despite virological failure, when these drugs are used as a component of combination antiretroviral therapy (cART), remains unclear.",
keywords = "Adult, Aged, Anti-HIV Agents, Benzoxazines, DNA Mutational Analysis, Drug Resistance, Viral, Female, HIV Infections, Humans, Male, Middle Aged, Mutation, Nevirapine, Prospective Studies, Reverse Transcriptase Inhibitors, Viral Load, Young Adult",
author = "A Cozzi-Lepri and Paredes and Phillips, {A N} and B Clotet and J Kjaer and {Von Wyl}, V and Gitte Kronborg and A Castagna and Bogner, {J R} and Lundgren, {Jens Dilling} and {EuroSIDA in EuroCoord}",
note = "{\circledC} 2011 British HIV Association.",
year = "2012",
doi = "10.1111/j.1468-1293.2011.00943.x",
language = "English",
volume = "13",
pages = "62--72",
journal = "HIV Medicine",
issn = "1464-2662",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*

AU - Cozzi-Lepri, A

AU - Paredes, null

AU - Phillips, A N

AU - Clotet, B

AU - Kjaer, J

AU - Von Wyl, V

AU - Kronborg, Gitte

AU - Castagna, A

AU - Bogner, J R

AU - Lundgren, Jens Dilling

AU - EuroSIDA in EuroCoord

N1 - © 2011 British HIV Association.

PY - 2012

Y1 - 2012

N2 - Virological failure of first-generation nonnucleoside reverse transcriptase inhibitors (NNRTIs) can compromise the efficacy of etravirine as a result of the accumulation of NNRTI resistance mutations. How quickly NNRTI resistance accumulates in patients with a delayed switch from nevirapine or efavirenz despite virological failure, when these drugs are used as a component of combination antiretroviral therapy (cART), remains unclear.

AB - Virological failure of first-generation nonnucleoside reverse transcriptase inhibitors (NNRTIs) can compromise the efficacy of etravirine as a result of the accumulation of NNRTI resistance mutations. How quickly NNRTI resistance accumulates in patients with a delayed switch from nevirapine or efavirenz despite virological failure, when these drugs are used as a component of combination antiretroviral therapy (cART), remains unclear.

KW - Adult

KW - Aged

KW - Anti-HIV Agents

KW - Benzoxazines

KW - DNA Mutational Analysis

KW - Drug Resistance, Viral

KW - Female

KW - HIV Infections

KW - Humans

KW - Male

KW - Middle Aged

KW - Mutation

KW - Nevirapine

KW - Prospective Studies

KW - Reverse Transcriptase Inhibitors

KW - Viral Load

KW - Young Adult

U2 - 10.1111/j.1468-1293.2011.00943.x

DO - 10.1111/j.1468-1293.2011.00943.x

M3 - Journal article

VL - 13

SP - 62

EP - 72

JO - HIV Medicine

JF - HIV Medicine

SN - 1464-2662

IS - 1

ER -

ID: 36457275