Virus-associated changes of the cervix uteri were assessed in patients treated for grade 1 cervical intra-epithelial neoplasia (CIN). Of 106 patients evaluated, 67 (63%) had virus-associated changes. The patients were treated without regard to the presence/absence of virus-associated changes. In 26 patients the treatment was unsuccessful (persistence, recurrence, or progression of the neoplasia). The frequency of treatment failure was 33% in patients with, and 10% in patients without virus-associated changes (p less than 0.025). It is recommended that patients with CIN 1 and virus-associated changes should, after initial treatment, be followed-up with increased attention.
|Journal||Acta Obstetricia et Gynecologica Scandinavica|
|Number of pages||3|
|Publication status||Published - 1987|
- Middle Aged
- Uterine Cervical Neoplasms
- Virus Diseases