The presence of the d3-growth hormone receptor polymorphism is negatively associated with fetal growth but positively associated with postnatal growth in healthy subjects

Rikke Beck Jensen, Signe Vielwerth, Torben Kjeldgaard Larsen, Gorm Greisen, Henrik Leffers, Anders Juul

44 Citations (Scopus)

Abstract

A common polymorphism in the GH receptor (GHR) gene has been linked to increased growth response in GH-treated patients. No former study has focused on the association to prenatal growth.
Original languageEnglish
JournalJournal of Clinical Endocrinology and Metabolism
Volume92
Issue number7
Pages (from-to)2758-63
Number of pages6
ISSN0021-972X
DOIs
Publication statusPublished - 2007

Keywords

  • Adolescent
  • Adolescent Development
  • Birth Weight
  • Cohort Studies
  • Female
  • Fetal Development
  • Gestational Age
  • Heterozygote
  • Homozygote
  • Humans
  • Infant, Newborn
  • Infant, Small for Gestational Age
  • Male
  • Polymorphism, Genetic
  • Pregnancy
  • Prevalence
  • Prospective Studies
  • Receptors, Somatotropin

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