TY - JOUR
T1 - The potential of antimicrobials to induce thrombocytopenia in critically ill patients
T2 - data from a randomized controlled trial
AU - Johansen, Maria Egede
AU - Jensen, Jens Ulrik
AU - Bestle, Morten Heiberg
AU - Hein, Lars
AU - Lauritsen, Anne Øberg
AU - Tousi, Hamid
AU - Larsen, Kim Michael
AU - Løken, Jesper
AU - Mohr, Thomas
AU - Thormar, Katrin
AU - Johansson, Pär I
AU - Cozzi-Lepri, Alessandro
AU - Lundgren, Jens D
N1 - The Potential of Antimicrobials to Induce
Thrombocytopenia in Critically Ill Patients: Data from a
Randomized Controlled Trial
Maria Egede Johansen1*, Jens-Ulrik Jensen1,2, Morten Heiberg Bestle3
, Lars Hein3
, Anne Øberg
Lauritsen4
, Hamid Tousi5
, Kim Michael Larsen6
, Jesper Løken7
, Thomas Mohr8
, Katrin Thormar8,9, Pär I.
Johansson10,11, Alessandro Cozzi-Lepri12, Jens D. Lundgren1,13
1 Copenhagen HIV Programme at Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, 2 Department of Clinical Microbiology, Hvidovre University
Hospital, Hvidovre, Denmark, 3 Department of Anesthesia and Intensive Care, North Zealand University Hospital, Hillerod, Denmark, 4 Department of
Anesthesia and Intensive Care, Glostrup University Hospital, Glostrup, Denmark, 5 Department of Anesthesia and Intensive Care, Herlev University Hospital,
Herlev, Denmark, 6 Department of Anesthesia and Intensive Care, Aarhus University Hospital, Aarhus, Denmark, 7 Department of Anesthesia and Intensive
Care, Hvidovre University Hospital, Hvidovre, Denmark, 8 Department of Anesthesia and Intensive Care, Gentofte University Hospital, Gentofte, Denmark,
9 Department of Anesthesia and Intensive Care, Bispebjerg University Hospital, Copenhagen, Denmark, 10 Department of Transfusion Medicine and Capital
Region Blood Bank, University Hospital Rigshospitalet, Copenhagen, Denmark, 11 Department of Surgery, University of Texas Medical School, Houston, Texas,
United States of America, 12 Department of Virology, Royal Free and University College Medical School, London, United Kingdom, 13 Department of Infectious
Diseases, University Hospital Rigshospitalet, Copenhagen, Denmark
Abstract
Background: Antimicrobial-induced thrombocytopenia is frequently described in the literature among critically ill
PY - 2013
Y1 - 2013
N2 - Antimicrobial-induced thrombocytopenia is frequently described in the literature among critically ill patients. Several antimicrobials have been implicated, although experimental evidence to demonstrate causality is limited. We report, using a randomized trial, the potential of antimicrobials to induce thrombocytopenia.
AB - Antimicrobial-induced thrombocytopenia is frequently described in the literature among critically ill patients. Several antimicrobials have been implicated, although experimental evidence to demonstrate causality is limited. We report, using a randomized trial, the potential of antimicrobials to induce thrombocytopenia.
UR - https://www.scopus.com/pages/publications/84896698600
U2 - 10.1371/journal.pone.0081477
DO - 10.1371/journal.pone.0081477
M3 - Journal article
C2 - 24312305
SN - 1932-6203
VL - 8
SP - e81477
JO - P L o S One
JF - P L o S One
IS - 11
ER -