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The possible prognostic value of serum prolactin increment during pregnancy in hyperprolactinaemic patients

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  1. Urinary growth hormone excretion in acromegaly: diagnostic value in mild disease activity

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  2. Impaired pancreatic polypeptide response to a meal in type 1 diabetic patients: vagal neuropathy or islet cell dysfunction?

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  3. Bone metabolism in obesity: changes related to severe overweight and dietary weight reduction.

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  4. Effects of thyrotropin-releasing hormone on regional cerebral blood flow in man

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  1. Multivitamin intake does not affect the risk of preterm and very preterm birth

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  2. Hippo signaling, actin polymerization, and follicle activation in fragmented human ovarian cortex

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  3. Multivitamin use and risk of preeclampsia in a high-income population: A cohort study

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In 15 hyperprolactinaemic, infertile patients achieving 17 bromocriptine-induced pregnancies, the presence or absence of prolactin (Prl) increment in the 3rd trimester of pregnancy was correlated to the basal Prl levels before treatment and after pregnancy. The hyperprolactinaemic patients revealed a marked heterogeneity in the Prl increment compared to normal women. Five patients showed a pronounced increase in serum Prl during gestation, whereas Prl levels were unaltered or decreased slightly in 10 patients. In the latter group of patients serum Prl was significantly (P less than 0.01) lower after pregnancy than before treatment. Our study indicates that some hyperprolactinaemic patients may benefit from a pregnancy, and that these patients probably can be identified, as they do not show any significant changes in Prl levels during pregnancy.

Original languageEnglish
JournalActa Endocrinologica
Volume102
Issue number1
Pages (from-to)1-5
Number of pages5
ISSN0001-5598
Publication statusPublished - Jan 1983

    Research areas

  • Adenoma, Adult, Bromocriptine, Female, Humans, Infertility, Female, Pituitary Neoplasms, Postpartum Period, Pregnancy, Pregnancy Complications, Prognosis, Prolactin, Journal Article

ID: 53710805