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The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis

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Harvard

Smith, TO, Hawker, GA, Hunter, DJ, March, LM, Boers, M, Shea, BJ, Christensen, R, Guillemin, F, Terwee, CB, Williamson, PR, Dodd, S, Roos, EM, Loeser, RF, Schnitzer, TJ, Kloppenburg, M, Neogi, T, Ladel, CH, Kalsi, G, Kaiser, U, Buttel, TW, Ashford, AE, Mobasheri, A, Arden, NK, Tennant, A, Hochberg, MC, de Wit, M, Tugwell, P & Conaghan, PG 2019, 'The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis' Journal of Rheumatology, vol. 46, no. 8, pp. 981-989. https://doi.org/10.3899/jrheum.181194

APA

Smith, T. O., Hawker, G. A., Hunter, D. J., March, L. M., Boers, M., Shea, B. J., ... Conaghan, P. G. (2019). The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis. Journal of Rheumatology, 46(8), 981-989. https://doi.org/10.3899/jrheum.181194

CBE

Smith TO, Hawker GA, Hunter DJ, March LM, Boers M, Shea BJ, Christensen R, Guillemin F, Terwee CB, Williamson PR, Dodd S, Roos EM, Loeser RF, Schnitzer TJ, Kloppenburg M, Neogi T, Ladel CH, Kalsi G, Kaiser U, Buttel TW, Ashford AE, Mobasheri A, Arden NK, Tennant A, Hochberg MC, de Wit M, Tugwell P, Conaghan PG. 2019. The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis. Journal of Rheumatology. 46(8):981-989. https://doi.org/10.3899/jrheum.181194

MLA

Vancouver

Author

Smith, Toby O ; Hawker, Gillian A ; Hunter, David J ; March, Lyn M ; Boers, Maarten ; Shea, Beverley J ; Christensen, Robin ; Guillemin, Francis ; Terwee, Caroline B ; Williamson, Paula R ; Dodd, Susanna ; Roos, Ewa M ; Loeser, Richard F ; Schnitzer, Thomas J ; Kloppenburg, Margreet ; Neogi, Tuhina ; Ladel, Christoph H ; Kalsi, Gurdyal ; Kaiser, Ulrike ; Buttel, Thomas W ; Ashford, Anne E ; Mobasheri, Ali ; Arden, Nigel K ; Tennant, Alan ; Hochberg, Marc C ; de Wit, Maarten ; Tugwell, Peter ; Conaghan, Philip G. / The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis. In: Journal of Rheumatology. 2019 ; Vol. 46, No. 8. pp. 981-989.

Bibtex

@article{b6599f89bbec4117a68d3fd1ef25d4c8,
title = "The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis",
abstract = "OBJECTIVE: To update the 1997 OMERACT-OARSI (Outcome Measures in Rheumatology-Osteoarthritis Research Society International) core domain set for clinical trials in hip and/or knee osteoarthritis (OA).METHODS: An initial review of the COMET database of core outcome sets (COS) was undertaken to identify all domains reported in previous COS including individuals with hip and/or knee OA. These were presented during 5 patient and health professionals/researcher meetings in 3 continents (Europe, Australasia, North America). A 3-round international Delphi survey was then undertaken among patients, healthcare professionals, researchers, and industry representatives to gain consensus on key domains to be included in a core domain set for hip and/or knee OA. Findings were presented and discussed in small groups at OMERACT 2018, where consensus was obtained in the final plenary.RESULTS: Four previous COS were identified. Using these, and the patient and health professionals/researcher meetings, 50 potential domains formed the Delphi survey. There were 426 individuals from 25 different countries who contributed to the Delphi exercise. OMERACT 2018 delegates (n = 129) voted on candidate domains. Six domains gained agreement as mandatory to be measured and reported in all hip and/or knee OA clinical trials: pain, physical function, quality of life, and patient's global assessment of the target joint, in addition to the mandated core domain of adverse events including mortality. Joint structure was agreed as mandatory in specific circumstances, i.e., depending on the intervention.CONCLUSION: The updated core domain set for hip and/or knee OA has been agreed upon. Work will commence to determine which outcome measurement instrument should be recommended to cover each core domain.",
author = "Smith, {Toby O} and Hawker, {Gillian A} and Hunter, {David J} and March, {Lyn M} and Maarten Boers and Shea, {Beverley J} and Robin Christensen and Francis Guillemin and Terwee, {Caroline B} and Williamson, {Paula R} and Susanna Dodd and Roos, {Ewa M} and Loeser, {Richard F} and Schnitzer, {Thomas J} and Margreet Kloppenburg and Tuhina Neogi and Ladel, {Christoph H} and Gurdyal Kalsi and Ulrike Kaiser and Buttel, {Thomas W} and Ashford, {Anne E} and Ali Mobasheri and Arden, {Nigel K} and Alan Tennant and Hochberg, {Marc C} and {de Wit}, Maarten and Peter Tugwell and Conaghan, {Philip G}",
year = "2019",
month = "8",
doi = "10.3899/jrheum.181194",
language = "English",
volume = "46",
pages = "981--989",
journal = "Journal of Rheumatology",
issn = "0315-162X",
publisher = "Journal of Rheumatology Publishing Co. Ltd",
number = "8",

}

RIS

TY - JOUR

T1 - The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis

AU - Smith, Toby O

AU - Hawker, Gillian A

AU - Hunter, David J

AU - March, Lyn M

AU - Boers, Maarten

AU - Shea, Beverley J

AU - Christensen, Robin

AU - Guillemin, Francis

AU - Terwee, Caroline B

AU - Williamson, Paula R

AU - Dodd, Susanna

AU - Roos, Ewa M

AU - Loeser, Richard F

AU - Schnitzer, Thomas J

AU - Kloppenburg, Margreet

AU - Neogi, Tuhina

AU - Ladel, Christoph H

AU - Kalsi, Gurdyal

AU - Kaiser, Ulrike

AU - Buttel, Thomas W

AU - Ashford, Anne E

AU - Mobasheri, Ali

AU - Arden, Nigel K

AU - Tennant, Alan

AU - Hochberg, Marc C

AU - de Wit, Maarten

AU - Tugwell, Peter

AU - Conaghan, Philip G

PY - 2019/8

Y1 - 2019/8

N2 - OBJECTIVE: To update the 1997 OMERACT-OARSI (Outcome Measures in Rheumatology-Osteoarthritis Research Society International) core domain set for clinical trials in hip and/or knee osteoarthritis (OA).METHODS: An initial review of the COMET database of core outcome sets (COS) was undertaken to identify all domains reported in previous COS including individuals with hip and/or knee OA. These were presented during 5 patient and health professionals/researcher meetings in 3 continents (Europe, Australasia, North America). A 3-round international Delphi survey was then undertaken among patients, healthcare professionals, researchers, and industry representatives to gain consensus on key domains to be included in a core domain set for hip and/or knee OA. Findings were presented and discussed in small groups at OMERACT 2018, where consensus was obtained in the final plenary.RESULTS: Four previous COS were identified. Using these, and the patient and health professionals/researcher meetings, 50 potential domains formed the Delphi survey. There were 426 individuals from 25 different countries who contributed to the Delphi exercise. OMERACT 2018 delegates (n = 129) voted on candidate domains. Six domains gained agreement as mandatory to be measured and reported in all hip and/or knee OA clinical trials: pain, physical function, quality of life, and patient's global assessment of the target joint, in addition to the mandated core domain of adverse events including mortality. Joint structure was agreed as mandatory in specific circumstances, i.e., depending on the intervention.CONCLUSION: The updated core domain set for hip and/or knee OA has been agreed upon. Work will commence to determine which outcome measurement instrument should be recommended to cover each core domain.

AB - OBJECTIVE: To update the 1997 OMERACT-OARSI (Outcome Measures in Rheumatology-Osteoarthritis Research Society International) core domain set for clinical trials in hip and/or knee osteoarthritis (OA).METHODS: An initial review of the COMET database of core outcome sets (COS) was undertaken to identify all domains reported in previous COS including individuals with hip and/or knee OA. These were presented during 5 patient and health professionals/researcher meetings in 3 continents (Europe, Australasia, North America). A 3-round international Delphi survey was then undertaken among patients, healthcare professionals, researchers, and industry representatives to gain consensus on key domains to be included in a core domain set for hip and/or knee OA. Findings were presented and discussed in small groups at OMERACT 2018, where consensus was obtained in the final plenary.RESULTS: Four previous COS were identified. Using these, and the patient and health professionals/researcher meetings, 50 potential domains formed the Delphi survey. There were 426 individuals from 25 different countries who contributed to the Delphi exercise. OMERACT 2018 delegates (n = 129) voted on candidate domains. Six domains gained agreement as mandatory to be measured and reported in all hip and/or knee OA clinical trials: pain, physical function, quality of life, and patient's global assessment of the target joint, in addition to the mandated core domain of adverse events including mortality. Joint structure was agreed as mandatory in specific circumstances, i.e., depending on the intervention.CONCLUSION: The updated core domain set for hip and/or knee OA has been agreed upon. Work will commence to determine which outcome measurement instrument should be recommended to cover each core domain.

U2 - 10.3899/jrheum.181194

DO - 10.3899/jrheum.181194

M3 - Journal article

VL - 46

SP - 981

EP - 989

JO - Journal of Rheumatology

JF - Journal of Rheumatology

SN - 0315-162X

IS - 8

ER -

ID: 57855268