The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis

Walter P Maksymowych; Andrew McReynolds; Susanne J Pedersen; Ulrich Weber; Joel Paschke; Stephanie Wichuk; Jacob L Jaremko; Robert G Lambert

doi:10.1016/j.semarthrit.2021.05.014

The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis

Walter P Maksymowych, Andrew McReynolds, Susanne J Pedersen, Ulrich Weber, Joel Paschke, Stephanie Wichuk, Jacob L Jaremko, Robert G Lambert

Department for Rheumatology and Spine Diseases

7 Citations (Scopus)

Abstract

OBJECTIVE: To validate a revised version of the KIMRISS method for quantification of BML and synovitis-effusion in the knee by comparison with an established method, MOAKS.

METHODS: Novel calibration tools were developed for both methods. We compared reliability for status and change scores of BML and synovitis-effusion on baseline and one-year MRI scans.

RESULTS: Significant increase in both BML and synovitis-effusion was evident using KIMRISS but only for synovitis-effusion using MOAKS. Pre-specified targets for acceptable reliability (≥0.80 and ≥0.70 for status and change scores, respectively) were achieved more frequently for KIMRISS for both BML and synovitis.

CONCLUSION: Per OFISA criteria, KIMRISS should progress to assessment of discrimination.

Original language	English
Journal	Seminars in Arthritis and Rheumatism
Volume	51
Issue number	4
Pages (from-to)	925-928
Number of pages	4
ISSN	0049-0172
DOIs	https://doi.org/10.1016/j.semarthrit.2021.05.014
Publication status	Published - Aug 2021

Keywords

Bone marrow lesions
Knee inflammation MRI scoring system (KIMRISS)
MRI
OMERACT
Osteoarthritis

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10.1016/j.semarthrit.2021.05.014

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Maksymowych, W. P., McReynolds, A., Pedersen, S. J., Weber, U., Paschke, J., Wichuk, S., Jaremko, J. L., & Lambert, R. G. (2021). The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis. Seminars in Arthritis and Rheumatism, 51(4), 925-928. https://doi.org/10.1016/j.semarthrit.2021.05.014

The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis. / Maksymowych, Walter P; McReynolds, Andrew; Pedersen, Susanne J et al.
In: Seminars in Arthritis and Rheumatism, Vol. 51, No. 4, 08.2021, p. 925-928.

Research output: Contribution to journal › Journal article › Research › peer-review

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title = "The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis",

abstract = "OBJECTIVE: To validate a revised version of the KIMRISS method for quantification of BML and synovitis-effusion in the knee by comparison with an established method, MOAKS.METHODS: Novel calibration tools were developed for both methods. We compared reliability for status and change scores of BML and synovitis-effusion on baseline and one-year MRI scans.RESULTS: Significant increase in both BML and synovitis-effusion was evident using KIMRISS but only for synovitis-effusion using MOAKS. Pre-specified targets for acceptable reliability (≥0.80 and ≥0.70 for status and change scores, respectively) were achieved more frequently for KIMRISS for both BML and synovitis.CONCLUSION: Per OFISA criteria, KIMRISS should progress to assessment of discrimination.",

keywords = "Bone marrow lesions, Knee inflammation MRI scoring system (KIMRISS), MRI, OMERACT, Osteoarthritis",

author = "Maksymowych, \{Walter P\} and Andrew McReynolds and Pedersen, \{Susanne J\} and Ulrich Weber and Joel Paschke and Stephanie Wichuk and Jaremko, \{Jacob L\} and Lambert, \{Robert G\}",

year = "2021",

month = aug,

doi = "10.1016/j.semarthrit.2021.05.014",

language = "English",

volume = "51",

pages = "925--928",

journal = "Seminars in Arthritis and Rheumatism",

issn = "0049-0172",

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T1 - The OMERACT Knee Inflammation MRI Scoring System

T2 - Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis

AU - Maksymowych, Walter P

AU - McReynolds, Andrew

AU - Pedersen, Susanne J

AU - Weber, Ulrich

AU - Paschke, Joel

AU - Wichuk, Stephanie

AU - Jaremko, Jacob L

AU - Lambert, Robert G

PY - 2021/8

Y1 - 2021/8

N2 - OBJECTIVE: To validate a revised version of the KIMRISS method for quantification of BML and synovitis-effusion in the knee by comparison with an established method, MOAKS.METHODS: Novel calibration tools were developed for both methods. We compared reliability for status and change scores of BML and synovitis-effusion on baseline and one-year MRI scans.RESULTS: Significant increase in both BML and synovitis-effusion was evident using KIMRISS but only for synovitis-effusion using MOAKS. Pre-specified targets for acceptable reliability (≥0.80 and ≥0.70 for status and change scores, respectively) were achieved more frequently for KIMRISS for both BML and synovitis.CONCLUSION: Per OFISA criteria, KIMRISS should progress to assessment of discrimination.

AB - OBJECTIVE: To validate a revised version of the KIMRISS method for quantification of BML and synovitis-effusion in the knee by comparison with an established method, MOAKS.METHODS: Novel calibration tools were developed for both methods. We compared reliability for status and change scores of BML and synovitis-effusion on baseline and one-year MRI scans.RESULTS: Significant increase in both BML and synovitis-effusion was evident using KIMRISS but only for synovitis-effusion using MOAKS. Pre-specified targets for acceptable reliability (≥0.80 and ≥0.70 for status and change scores, respectively) were achieved more frequently for KIMRISS for both BML and synovitis.CONCLUSION: Per OFISA criteria, KIMRISS should progress to assessment of discrimination.

KW - Bone marrow lesions

KW - Knee inflammation MRI scoring system (KIMRISS)

KW - MRI

KW - OMERACT

KW - Osteoarthritis

UR - https://www.scopus.com/pages/publications/85108512452

U2 - 10.1016/j.semarthrit.2021.05.014

DO - 10.1016/j.semarthrit.2021.05.014

M3 - Journal article

C2 - 34167825

SN - 0049-0172

VL - 51

SP - 925

EP - 928

JO - Seminars in Arthritis and Rheumatism

JF - Seminars in Arthritis and Rheumatism

IS - 4

ER -

The OMERACT Knee Inflammation MRI Scoring System: Validation of quantitative methodologies and tri-compartmental overlays in osteoarthritis

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Keywords

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