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The Capital Region of Denmark - a part of Copenhagen University Hospital
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The number of regulatory T cells in transbronchial lung allograft biopsies is related to FoxP3 mRNA levels in bronchoalveolar lavage fluid and to the degree of acute cellular rejection

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  1. Elevated mRNA levels of CTLA-4, FoxP3, and granzyme B in BAL, but not in blood, during acute rejection of lung allografts

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Cytomegalovirus-specific CD8+ T-cell responses are associated with arterial blood pressure in people living with HIV

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Rare non-coding Desmoglein-2 variant contributes to Arrhythmogenic right ventricular cardiomyopathy

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  3. Collagen density regulates the activity of tumor-infiltrating T cells

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The transcription factor Forkhead Box P3 (FoxP3) is a marker of regulatory T cells (Tregs) - a subset of T cells known to suppress a wide range of immune responses. These cells are considered to be pivotal for the induction of tolerance to donor antigens in human allografts. We aimed to correlate the number of lymphocytes expressing FoxP3 in transbronchial biopsies from lung allografts with the FoxP3 expression in bronchoalveolar lavage fluid (BALF). In addition, we aimed to correlate the number of FoxP3+ cells in transbronchial biopsies with the degree of acute cellular rejection in lung allografts.
Original languageEnglish
JournalTransplant Immunology
Issue number1-4
Pages (from-to)71-5
ISSN0966-3274
DOIs
Publication statusPublished - 19 Aug 2013

ID: 39009481