The Nordic aortic valve intervention (NOTION) trial comparing transcatheter versus surgical valve implantation: study protocol for a randomised controlled trial

Hans Gustav Thyregod; Lars Søndergaard; Nikolaj Ihlemann; Olaf Franzen; Lars Willy Andersen; Peter Bo Hansen; Peter Skov Olsen; Henrik Hoffmann Nissen; Per Winkel; Christian Gluud; Daniel Andreas Steinbrüchel

doi:10.1186/1745-6215-14-11

The Nordic aortic valve intervention (NOTION) trial comparing transcatheter versus surgical valve implantation: study protocol for a randomised controlled trial

Hans Gustav Thyregod, Lars Søndergaard, Nikolaj Ihlemann, Olaf Franzen, Lars Willy Andersen, Peter Bo Hansen, Peter Skov Olsen, Henrik Hoffmann Nissen, Per Winkel, Christian Gluud, Daniel Andreas Steinbrüchel

Copenhagen Trial Unit

51 Citations (Scopus)

Abstract

Degenerative aortic valve (AV) stenosis is the most prevalent heart valve disease in the western world. Surgical aortic valve replacement (SAVR) has until recently been the standard of treatment for patients with severe AV stenosis. Whether transcatheter aortic valve implantation (TAVI) can be offered with improved safety and similar effectiveness in a population including low-risk patients has yet to be examined in a randomised setting.

Original language	English
Journal	Trials
Volume	14
Pages (from-to)	11
ISSN	1745-6215
DOIs	https://doi.org/10.1186/1745-6215-14-11
Publication status	Published - 2013

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Thyregod, H. G., Søndergaard, L., Ihlemann, N., Franzen, O., Andersen, L. W., Hansen, P. B., Olsen, P. S., Nissen, H. H., Winkel, P., Gluud, C., & Steinbrüchel, D. A. (2013). The Nordic aortic valve intervention (NOTION) trial comparing transcatheter versus surgical valve implantation: study protocol for a randomised controlled trial. Trials, 14, 11. https://doi.org/10.1186/1745-6215-14-11

Thyregod, HG , Søndergaard, L , Ihlemann, N, Franzen, O, Andersen, LW, Hansen, PB , Olsen, PS, Nissen, HH, Winkel, P, Gluud, C & Steinbrüchel, DA 2013, 'The Nordic aortic valve intervention (NOTION) trial comparing transcatheter versus surgical valve implantation: study protocol for a randomised controlled trial', Trials, vol. 14, pp. 11. https://doi.org/10.1186/1745-6215-14-11

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abstract = "Degenerative aortic valve (AV) stenosis is the most prevalent heart valve disease in the western world. Surgical aortic valve replacement (SAVR) has until recently been the standard of treatment for patients with severe AV stenosis. Whether transcatheter aortic valve implantation (TAVI) can be offered with improved safety and similar effectiveness in a population including low-risk patients has yet to be examined in a randomised setting.",

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AU - Thyregod, Hans Gustav

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AU - Ihlemann, Nikolaj

AU - Franzen, Olaf

AU - Andersen, Lars Willy

AU - Hansen, Peter Bo

AU - Olsen, Peter Skov

AU - Nissen, Henrik Hoffmann

AU - Winkel, Per

AU - Gluud, Christian

AU - Steinbrüchel, Daniel Andreas

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AB - Degenerative aortic valve (AV) stenosis is the most prevalent heart valve disease in the western world. Surgical aortic valve replacement (SAVR) has until recently been the standard of treatment for patients with severe AV stenosis. Whether transcatheter aortic valve implantation (TAVI) can be offered with improved safety and similar effectiveness in a population including low-risk patients has yet to be examined in a randomised setting.

UR - https://www.scopus.com/pages/publications/84872037856

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The Nordic aortic valve intervention (NOTION) trial comparing transcatheter versus surgical valve implantation: study protocol for a randomised controlled trial

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