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The Capital Region of Denmark - a part of Copenhagen University Hospital
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The influence of insulin on the raised plasma fibronectin concentration in human obesity

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  1. Thyroid hormones and thyroxine-binding globulin in relation to liver function and serum testosterone in men with alcoholic cirrhosis

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  2. Increased plasma fibronectin concentrations in obesity: normalization during weight loss

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  3. Home readings of blood pressure in assessment of hypertensive subjects

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  4. Autoantibodies and immunoglobulins in alcoholic steatosis and cirrhosis

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  5. Metabolic responses to hypoglycemia in juvenile diabetics

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  1. Acupuncture for chronic hepatitis B

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  2. Exercise-Based Rehabilitation for Heart Failure: Cochrane Systematic Review, Meta-Analysis, and Trial Sequential Analysis

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  3. Plasma expanders for people with cirrhosis and large ascites treated with abdominal paracentesis

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  4. Radix Sophorae flavescentis versus other drugs or herbs for chronic hepatitis B

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  5. Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years

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Plasma concentrations of fibronectin, free insulin, C-peptide and plasma glucose were determined in 40 morbidly obese subjects and in 51 normal weight controls, matched for sex and age. All plasma concentrations were significantly elevated (p less than 0.01) among the obese subjects. A significant correlation (r = 0.34, p less than 0.05) between plasma fibronectin and plasma free insulin was found among the obese patients, but not among the controls (r = -0.02, p greater than 0.05). No significant correlation was found between plasma fibronectin and plasma C-peptide, neither in the obese patients nor in the controls (obese r = 0.06, controls r = 0.02; p greater than 0.05). Plasma fibronectin was insignificantly correlated with body weight (obese r = 0.21, controls r = 0.15; p greater than 0.05) and percentage overweight (obese r = 0.27, controls r = 0.04; p greater than 0.05). The raised level of circulating insulin may in part explain the excess of plasma fibronectin obese subjects.
Original languageEnglish
JournalActa medica Scandinavica. Supplementum
Volume220
Issue number3
Pages (from-to)269-72
Number of pages4
ISSN0365-463X
Publication statusPublished - 1986

    Research areas

  • Adult, Blood Glucose, C-Peptide, Female, Fibronectins, Humans, Insulin, Male, Middle Aged, Obesity, Obesity, Morbid

ID: 38931043