Abstract
BACKGROUND
Persons born in non-western countries have a higher risk and earlier onset of type 2 diabetes (T2D) in Denmark
It is not well investigated how country of birth status among persons with early-onset T2D (18-45 years) influences the incidence of micro- and macrovascular complications
We aimed to calculate incidence rate ratios (IRR) of micro- and macrovascular complications among persons with early- onset T2D born in western and non-western countries compared to those born in Denmark
METHODS
Data was obtained from nationwide registers
A total of 42,926 Danish citizens diagnosed with T2D between 18-45 years were followed from 1996 to 2018 and classified as Danish, non-western or western
IRR of the first event of each complication was estimated using age and sex adjusted Poisson regression models comparing persons with T2D in relation to country of birth
RESULTS
10,248 (23.9%) developed CVD, 2,147 (5%) developed retinopathy, 3,750 (8.7%) developed nephropathy and 696 (1.6%) underwent an amputation during follow-up
Persons born in non-western countries had an increased risk of retinopathy compared to those born in Denmark, but a decreased risk of CVD, nephropathy and amputation (figure 1)
Persons born in western countries had an increased risk of retinopathy, a similar risk of nephropathy and a lower risk of CVD and amputation compared to those born in Denmark (figure 2)
CONCLUSION
Persons with early-onset T2D born in non-western or western countries had a slightly higher risk of retinopathy and a lower risk of CVD and amputation compared to those born in Denmark
Persons born in non-western countries have a higher risk and earlier onset of type 2 diabetes (T2D) in Denmark
It is not well investigated how country of birth status among persons with early-onset T2D (18-45 years) influences the incidence of micro- and macrovascular complications
We aimed to calculate incidence rate ratios (IRR) of micro- and macrovascular complications among persons with early- onset T2D born in western and non-western countries compared to those born in Denmark
METHODS
Data was obtained from nationwide registers
A total of 42,926 Danish citizens diagnosed with T2D between 18-45 years were followed from 1996 to 2018 and classified as Danish, non-western or western
IRR of the first event of each complication was estimated using age and sex adjusted Poisson regression models comparing persons with T2D in relation to country of birth
RESULTS
10,248 (23.9%) developed CVD, 2,147 (5%) developed retinopathy, 3,750 (8.7%) developed nephropathy and 696 (1.6%) underwent an amputation during follow-up
Persons born in non-western countries had an increased risk of retinopathy compared to those born in Denmark, but a decreased risk of CVD, nephropathy and amputation (figure 1)
Persons born in western countries had an increased risk of retinopathy, a similar risk of nephropathy and a lower risk of CVD and amputation compared to those born in Denmark (figure 2)
CONCLUSION
Persons with early-onset T2D born in non-western or western countries had a slightly higher risk of retinopathy and a lower risk of CVD and amputation compared to those born in Denmark
| Original language | Danish |
|---|---|
| Publication date | Apr 2022 |
| Publication status | Published - Apr 2022 |
| Event | European Diabetes Epidemiology Group - Creta Maris Hotel, Hersonissos, Greece Duration: 2 Apr 2022 → 5 Apr 2022 Conference number: 56 https://edeg2022.com/ |
Conference
| Conference | European Diabetes Epidemiology Group |
|---|---|
| Number | 56 |
| Location | Creta Maris Hotel |
| Country/Territory | Greece |
| City | Hersonissos |
| Period | 02/04/2022 → 05/04/2022 |
| Internet address |