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The impact of severe hypoglycemia and impaired awareness of hypoglycemia on relatives of patients with type 1 diabetes

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Jørgensen, Hanne V ; Pedersen-Bjergaard, Ulrik ; Rasmussen, Ase K ; Borch-Johnsen, Knut. / The impact of severe hypoglycemia and impaired awareness of hypoglycemia on relatives of patients with type 1 diabetes. In: Diabetes Care. 2003 ; Vol. 26, No. 4. pp. 1106-9.

Bibtex

@article{2ea70e88a2a843ea92c622916bd8edcf,
title = "The impact of severe hypoglycemia and impaired awareness of hypoglycemia on relatives of patients with type 1 diabetes",
abstract = "OBJECTIVE: Severe hypoglycemia is a major problem for patients with type 1 diabetes and their relatives. The aim of this study was to compare patients' and relatives' assessments of rates of severe hypoglycemia and state of awareness and to explore the influence on involvement and concern of relatives.RESEARCH DESIGN AND METHODS: A cross-sectional paired questionnaire survey on hypoglycemia and the state of awareness was used in our study comprising 284 unselected adult patients with type 1 diabetes and their closest cohabitant. The cohabitant questionnaires also addressed involvement and concern.RESULTS: The agreement between assessments of rates of severe hypoglycemia and state of awareness made by patients and cohabitants was weak (kappa 0.404 and 0.442, respectively; P < 0.001). Cohabitants recalled more episodes of severe hypoglycemia than patients (2.7 vs. 1.6 episodes/patient-year; P < 0.001). Degree of involvement was positively related to the rate of severe hypoglycemia (P = 0.002) and negatively related to the state of awareness (P = 0.007) but not to level of HbA(1c), duration of diabetes, or presence of late complications, except for peripheral neuropathy (P = 0.01).CONCLUSIONS: Cohabitants of patients with type 1 diabetes recall significantly more episodes of severe hypoglycemia than the patients. The rate of severe hypoglycemia and state of hypoglycemic awareness are the principal determinants of degree of cohabitants' involvement in their partners' disease.",
keywords = "Adult, Age of Onset, Attitude to Health, Awareness, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Family, Female, Hemoglobin A, Glycosylated, Humans, Hypoglycemia, Insulin, Male, Outpatients, Surveys and Questionnaires, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't",
author = "J{\o}rgensen, {Hanne V} and Ulrik Pedersen-Bjergaard and Rasmussen, {Ase K} and Knut Borch-Johnsen",
year = "2003",
month = apr,
language = "English",
volume = "26",
pages = "1106--9",
journal = "Diabetes Care",
issn = "1935-5548",
publisher = "American Diabetes Association",
number = "4",

}

RIS

TY - JOUR

T1 - The impact of severe hypoglycemia and impaired awareness of hypoglycemia on relatives of patients with type 1 diabetes

AU - Jørgensen, Hanne V

AU - Pedersen-Bjergaard, Ulrik

AU - Rasmussen, Ase K

AU - Borch-Johnsen, Knut

PY - 2003/4

Y1 - 2003/4

N2 - OBJECTIVE: Severe hypoglycemia is a major problem for patients with type 1 diabetes and their relatives. The aim of this study was to compare patients' and relatives' assessments of rates of severe hypoglycemia and state of awareness and to explore the influence on involvement and concern of relatives.RESEARCH DESIGN AND METHODS: A cross-sectional paired questionnaire survey on hypoglycemia and the state of awareness was used in our study comprising 284 unselected adult patients with type 1 diabetes and their closest cohabitant. The cohabitant questionnaires also addressed involvement and concern.RESULTS: The agreement between assessments of rates of severe hypoglycemia and state of awareness made by patients and cohabitants was weak (kappa 0.404 and 0.442, respectively; P < 0.001). Cohabitants recalled more episodes of severe hypoglycemia than patients (2.7 vs. 1.6 episodes/patient-year; P < 0.001). Degree of involvement was positively related to the rate of severe hypoglycemia (P = 0.002) and negatively related to the state of awareness (P = 0.007) but not to level of HbA(1c), duration of diabetes, or presence of late complications, except for peripheral neuropathy (P = 0.01).CONCLUSIONS: Cohabitants of patients with type 1 diabetes recall significantly more episodes of severe hypoglycemia than the patients. The rate of severe hypoglycemia and state of hypoglycemic awareness are the principal determinants of degree of cohabitants' involvement in their partners' disease.

AB - OBJECTIVE: Severe hypoglycemia is a major problem for patients with type 1 diabetes and their relatives. The aim of this study was to compare patients' and relatives' assessments of rates of severe hypoglycemia and state of awareness and to explore the influence on involvement and concern of relatives.RESEARCH DESIGN AND METHODS: A cross-sectional paired questionnaire survey on hypoglycemia and the state of awareness was used in our study comprising 284 unselected adult patients with type 1 diabetes and their closest cohabitant. The cohabitant questionnaires also addressed involvement and concern.RESULTS: The agreement between assessments of rates of severe hypoglycemia and state of awareness made by patients and cohabitants was weak (kappa 0.404 and 0.442, respectively; P < 0.001). Cohabitants recalled more episodes of severe hypoglycemia than patients (2.7 vs. 1.6 episodes/patient-year; P < 0.001). Degree of involvement was positively related to the rate of severe hypoglycemia (P = 0.002) and negatively related to the state of awareness (P = 0.007) but not to level of HbA(1c), duration of diabetes, or presence of late complications, except for peripheral neuropathy (P = 0.01).CONCLUSIONS: Cohabitants of patients with type 1 diabetes recall significantly more episodes of severe hypoglycemia than the patients. The rate of severe hypoglycemia and state of hypoglycemic awareness are the principal determinants of degree of cohabitants' involvement in their partners' disease.

KW - Adult

KW - Age of Onset

KW - Attitude to Health

KW - Awareness

KW - Cross-Sectional Studies

KW - Diabetes Mellitus, Type 1

KW - Family

KW - Female

KW - Hemoglobin A, Glycosylated

KW - Humans

KW - Hypoglycemia

KW - Insulin

KW - Male

KW - Outpatients

KW - Surveys and Questionnaires

KW - Journal Article

KW - Multicenter Study

KW - Research Support, Non-U.S. Gov't

M3 - Journal article

C2 - 12663581

VL - 26

SP - 1106

EP - 1109

JO - Diabetes Care

JF - Diabetes Care

SN - 1935-5548

IS - 4

ER -

ID: 51548502