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The Capital Region of Denmark - a part of Copenhagen University Hospital
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The immunomodulatory effect of inhaled granulocyte-macrophage colony-stimulating factor in cystic fibrosis. A new treatment paradigm

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  1. Complement Profiles in Patients with Amyotrophic Lateral Sclerosis: A Prospective Observational Cohort Study

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  2. Release of active peptidylarginine deiminase into the circulation during acute inflammation induced by coronary artery bypass surgery

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  3. High-sensitivity C-reactive protein and exercise-induced changes in subjects suspected of coronary artery disease

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  1. Trochlearisparese grundet kronisk sinuitis

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  2. The sweet Christmas rash (case series)

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  3. Local pulmonary administration of factor VIIa (rFVIIa) in diffuse alveolar hemorrhage (DAH) - a review of a new treatment paradigm

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  4. Chronic mucus hypersecretion: a marker of asthma in young adults?

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Patients with cystic fibrosis (CF) experience recurrent infections and develop chronically infected lungs, which initiates an altered immunological alveolar environment. End-stage pulmonary dysfunction is a result of a long sequence of complex events in CF, progressing to alveolar macrophage dysfunction via a T-helper 2 (T(H)2) dominated alveolar inflammation with CD20 T-cell activation, induced by the chronic infection and showing a poor prognosis. There is great potential for treatment in transforming the T(H)2 into the more favorable T-helper 1 (T(H)1) response.
Original languageEnglish
JournalJournal of Inflammation Research
Volume5
Pages (from-to)19-27
Number of pages9
ISSN1178-7031
DOIs
Publication statusPublished - 2012

ID: 36744406