The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors

Kazuya Kondo; Paul Van Schil; Frank C Detterbeck; Meinoshin Okumura; Kelly Stratton; Dorothy Giroux; Hisao Asamura; John Crowley; Conrad Falkson; Pier Luigi Filosso; Giuseppe Giaccone; James Huang; Jhingook Kim; Marco Lucchi; Mirella Marino; Edith M Marom; Andrew G Nicholson; Enrico Ruffini; Staging and Prognostic Factors Committee; Gedske Daugaard

doi:10.1097/JTO.0000000000000291

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors

Kazuya Kondo
, Paul Van Schil
, Frank C Detterbeck
, Meinoshin Okumura
, Kelly Stratton
, Dorothy Giroux
, Hisao Asamura
, John Crowley
, Conrad Falkson
, Pier Luigi Filosso
, Giuseppe Giaccone
, James Huang
, Jhingook Kim
, Marco Lucchi
, Mirella Marino
, Edith M Marom
, Andrew G Nicholson
, Enrico Ruffini
, Staging and Prognostic Factors Committee
, Gedske Daugaard (Member of author group)

116 Citations (Scopus)

Abstract

Stage classification is an important underpinning of management of patients with cancer, and rests on a combination of three components: T for tumor extent, N for nodal involvement, and M for more distant metastases. This article details an initiative to develop proposals for the first official stage classification system for thymic malignancies for the 8th edition of the stage classification manuals. Specifically, the results of analysis of a large database and the considerations leading to the proposed N and M components are described. Nodal involvement is divided into an anterior (N1) and a deep (N2) category. Metastases can involve pleural or pericardial nodules (M1a) or intraparenchymal pulmonary nodules or metastases to distant sites (M1b).

Original language	English
Journal	Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
Volume	9
Issue number	9 Suppl 2
Pages (from-to)	S81-7
ISSN	1556-0864
DOIs	https://doi.org/10.1097/JTO.0000000000000291
Publication status	Published - Sept 2014
Externally published	Yes

Keywords

Humans
Lymphatic Metastasis
Neoplasm Metastasis
Neoplasm Staging
Neoplasms, Glandular and Epithelial/classification
Prognosis
Survival Analysis
Thymus Neoplasms/classification

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10.1097/JTO.0000000000000291

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Kondo, K., Van Schil, P., Detterbeck, F. C., Okumura, M., Stratton, K., Giroux, D., Asamura, H., Crowley, J., Falkson, C., Filosso, P. L., Giaccone, G., Huang, J., Kim, J., Lucchi, M., Marino, M., Marom, E. M., Nicholson, A. G., Ruffini, E., Staging and Prognostic Factors Committee, & Daugaard, G. (2014). The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 9(9 Suppl 2), S81-7. https://doi.org/10.1097/JTO.0000000000000291

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors. / Kondo, Kazuya; Van Schil, Paul; Detterbeck, Frank C et al.
In: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 9, No. 9 Suppl 2, 09.2014, p. S81-7.

Research output: Contribution to journal › Journal article › Research › peer-review

Kondo, K, Van Schil, P, Detterbeck, FC, Okumura, M, Stratton, K, Giroux, D, Asamura, H, Crowley, J, Falkson, C, Filosso, PL, Giaccone, G, Huang, J, Kim, J, Lucchi, M, Marino, M, Marom, EM, Nicholson, AG, Ruffini, E, Staging and Prognostic Factors Committee & Daugaard, G 2014, 'The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors', Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, vol. 9, no. 9 Suppl 2, pp. S81-7. https://doi.org/10.1097/JTO.0000000000000291

Kondo K, Van Schil P, Detterbeck FC, Okumura M, Stratton K, Giroux D et al. The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2014 Sept;9(9 Suppl 2):S81-7. doi: 10.1097/JTO.0000000000000291

Kondo, Kazuya ; Van Schil, Paul ; Detterbeck, Frank C et al. / The IASLC/ITMIG Thymic Epithelial Tumors Staging Project : proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors. In: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2014 ; Vol. 9, No. 9 Suppl 2. pp. S81-7.

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abstract = "Stage classification is an important underpinning of management of patients with cancer, and rests on a combination of three components: T for tumor extent, N for nodal involvement, and M for more distant metastases. This article details an initiative to develop proposals for the first official stage classification system for thymic malignancies for the 8th edition of the stage classification manuals. Specifically, the results of analysis of a large database and the considerations leading to the proposed N and M components are described. Nodal involvement is divided into an anterior (N1) and a deep (N2) category. Metastases can involve pleural or pericardial nodules (M1a) or intraparenchymal pulmonary nodules or metastases to distant sites (M1b).",

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AU - Falkson, Conrad

AU - Filosso, Pier Luigi

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AU - Kim, Jhingook

AU - Lucchi, Marco

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AU - Marom, Edith M

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AB - Stage classification is an important underpinning of management of patients with cancer, and rests on a combination of three components: T for tumor extent, N for nodal involvement, and M for more distant metastases. This article details an initiative to develop proposals for the first official stage classification system for thymic malignancies for the 8th edition of the stage classification manuals. Specifically, the results of analysis of a large database and the considerations leading to the proposed N and M components are described. Nodal involvement is divided into an anterior (N1) and a deep (N2) category. Metastases can involve pleural or pericardial nodules (M1a) or intraparenchymal pulmonary nodules or metastases to distant sites (M1b).

KW - Humans

KW - Lymphatic Metastasis

KW - Neoplasm Metastasis

KW - Neoplasm Staging

KW - Neoplasms, Glandular and Epithelial/classification

KW - Prognosis

KW - Survival Analysis

KW - Thymus Neoplasms/classification

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M3 - Journal article

C2 - 25396316

SN - 1556-0864

VL - 9

SP - S81-7

JO - Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

JF - Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

IS - 9 Suppl 2

ER -

The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors

Abstract

Keywords

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