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The Capital Region of Denmark - a part of Copenhagen University Hospital
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The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors

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  1. The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome

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  2. Tisotumab Vedotin in Previously Treated Recurrent or Metastatic Cervical Cancer

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  3. Clonotypic Diversity of the T-cell Receptor Corroborates the Immature Precursor Origin of Cutaneous T-cell Lymphoma

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  1. Mortality and admission to intensive care units after febrile neutropenia in patients with cancer

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  2. Machine learning can identify newly diagnosed patients with CLL at high risk of infection

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  3. Behandling af tymom og thymuskarcinom

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  4. EP1.08-07 Correlation Between Genetic Profiling and Response in Danish ALK-Positive NSCLC Patients Treated with Crizotinib

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Multiple myeloma SET (Suppressor of variegation, Enhancer of zeste, and Trithorax) domain (MMSET) is a histone lysine methyltransferase deregulated in a subgroup of multiple myelomas with the t(4;14)(p16;q32) translocation and poor prognosis. With the aim of understanding, if MMSET can be involved in other types of cancer we investigated the expression of MMSET protein in different types of human tumors.
Original languageEnglish
JournalClinical Cancer Research
Volume17
Issue number9
Pages (from-to)2919-33
Number of pages15
ISSN1078-0432
DOIs
Publication statusPublished - 2011

    Research areas

  • Animals, Antibodies, Monoclonal, Antibody Specificity, Female, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Histone-Lysine N-Methyltransferase, Humans, Male, Mice, Models, Biological, Neoplasms, Oncogene Proteins, Repressor Proteins, Tissue Array Analysis, Tumor Cells, Cultured, Up-Regulation

ID: 33222101