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The Capital Region of Denmark - a part of Copenhagen University Hospital
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The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors

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  1. Impact of Donor Type in Patients with AML Given Allogeneic Hematopoietic Cell Transplantation After Low-Dose TBI-Based Regimen

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  2. PD-1+ Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer

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  1. Acute sensory and motor response to 45-s heavy isometric holds for the plantar flexors in patients with Achilles tendinopathy

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  2. Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

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  3. Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors

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Multiple myeloma SET (Suppressor of variegation, Enhancer of zeste, and Trithorax) domain (MMSET) is a histone lysine methyltransferase deregulated in a subgroup of multiple myelomas with the t(4;14)(p16;q32) translocation and poor prognosis. With the aim of understanding, if MMSET can be involved in other types of cancer we investigated the expression of MMSET protein in different types of human tumors.
Original languageEnglish
JournalClinical Cancer Research
Volume17
Issue number9
Pages (from-to)2919-33
Number of pages15
ISSN1078-0432
DOIs
Publication statusPublished - 2011

    Research areas

  • Animals, Antibodies, Monoclonal, Antibody Specificity, Female, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Histone-Lysine N-Methyltransferase, Humans, Male, Mice, Models, Biological, Neoplasms, Oncogene Proteins, Repressor Proteins, Tissue Array Analysis, Tumor Cells, Cultured, Up-Regulation

ID: 33222101