The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management

Mary Jarden; Lis Adamsen; Lars Kjeldsen; Henrik Birgens; Anders Tolver; Jesper Frank Christensen; Merete Stensen; Vivi-Ann Sørensen; Tom Møller

doi:10.1016/j.leukres.2012.09.001

The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management

Mary Jarden, Lis Adamsen, Lars Kjeldsen, Henrik Birgens, Anders Tolver, Jesper Frank Christensen, Merete Stensen, Vivi-Ann Sørensen, Tom Møller

UCSF

24 Citations (Scopus)

Abstract

This study investigates the feasibility, safety and benefits of a 6-week exercise and health counseling intervention in patients with acute leukemia undergoing consolidation chemotherapy during outpatient management. Seventeen of twenty patients completed study requirements (85%), adherence to exercise was 73% and for health counseling 92%. There were improvements in the 6-min-walk-distance (p=0.0013), sit-to-stand test (p=0.0062), the right and left biceps arm-curl tests p=0.0002 and p=0.0002, respectively; health-related quality of life (p=0.0209) (FACT-An), vitality (p=0.0015), mental health (p=0.0471) and physical component scale (p=0.0295) (SF36). Significant reduction in the symptom burden (p=0.0021) and symptom interference on daily life activities (p=0.0069) (MDASI). No adverse reactions were observed.

Original language	English
Journal	Leukemia Research
Volume	37
Issue number	2
Pages (from-to)	155-61
ISSN	0145-2126
DOIs	https://doi.org/10.1016/j.leukres.2012.09.001
Publication status	Published - 2013

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10.1016/j.leukres.2012.09.001

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title = "The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management",

abstract = "This study investigates the feasibility, safety and benefits of a 6-week exercise and health counseling intervention in patients with acute leukemia undergoing consolidation chemotherapy during outpatient management. Seventeen of twenty patients completed study requirements (85%), adherence to exercise was 73% and for health counseling 92%. There were improvements in the 6-min-walk-distance (p=0.0013), sit-to-stand test (p=0.0062), the right and left biceps arm-curl tests p=0.0002 and p=0.0002, respectively; health-related quality of life (p=0.0209) (FACT-An), vitality (p=0.0015), mental health (p=0.0471) and physical component scale (p=0.0295) (SF36). Significant reduction in the symptom burden (p=0.0021) and symptom interference on daily life activities (p=0.0069) (MDASI). No adverse reactions were observed.",

author = "Mary Jarden and Lis Adamsen and Lars Kjeldsen and Henrik Birgens and Anders Tolver and Christensen, {Jesper Frank} and Merete Stensen and Vivi-Ann S{\o}rensen and Tom M{\o}ller",

year = "2013",

doi = "10.1016/j.leukres.2012.09.001",

language = "English",

volume = "37",

pages = "155--61",

journal = "Leukemia Research",

issn = "0145-2126",

publisher = "Pergamon",

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TY - JOUR

T1 - The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management

AU - Jarden, Mary

AU - Adamsen, Lis

AU - Kjeldsen, Lars

AU - Birgens, Henrik

AU - Tolver, Anders

AU - Christensen, Jesper Frank

AU - Stensen, Merete

AU - Sørensen, Vivi-Ann

AU - Møller, Tom

PY - 2013

Y1 - 2013

N2 - This study investigates the feasibility, safety and benefits of a 6-week exercise and health counseling intervention in patients with acute leukemia undergoing consolidation chemotherapy during outpatient management. Seventeen of twenty patients completed study requirements (85%), adherence to exercise was 73% and for health counseling 92%. There were improvements in the 6-min-walk-distance (p=0.0013), sit-to-stand test (p=0.0062), the right and left biceps arm-curl tests p=0.0002 and p=0.0002, respectively; health-related quality of life (p=0.0209) (FACT-An), vitality (p=0.0015), mental health (p=0.0471) and physical component scale (p=0.0295) (SF36). Significant reduction in the symptom burden (p=0.0021) and symptom interference on daily life activities (p=0.0069) (MDASI). No adverse reactions were observed.

AB - This study investigates the feasibility, safety and benefits of a 6-week exercise and health counseling intervention in patients with acute leukemia undergoing consolidation chemotherapy during outpatient management. Seventeen of twenty patients completed study requirements (85%), adherence to exercise was 73% and for health counseling 92%. There were improvements in the 6-min-walk-distance (p=0.0013), sit-to-stand test (p=0.0062), the right and left biceps arm-curl tests p=0.0002 and p=0.0002, respectively; health-related quality of life (p=0.0209) (FACT-An), vitality (p=0.0015), mental health (p=0.0471) and physical component scale (p=0.0295) (SF36). Significant reduction in the symptom burden (p=0.0021) and symptom interference on daily life activities (p=0.0069) (MDASI). No adverse reactions were observed.

U2 - 10.1016/j.leukres.2012.09.001

DO - 10.1016/j.leukres.2012.09.001

M3 - Journal article

C2 - 23021021

VL - 37

SP - 155

EP - 161

JO - Leukemia Research

JF - Leukemia Research

SN - 0145-2126

IS - 2

ER -

The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management

Abstract

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