The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis

Kasper Aanaes; Christian von Buchwald; Thomas Hjuler; Marianne Skov; Mikkel Alanin; Helle Krogh Johansen

doi:10.2500/ajra.2013.27.3829

The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis

Kasper Aanaes, Christian von Buchwald, Thomas Hjuler, Marianne Skov, Mikkel Alanin, Helle Krogh Johansen

45 Citations (Scopus)

Abstract

Most patients with cystic fibrosis (CF) have chronic rhinosinusitis; their sinuses are often colonized with bacteria that can initiate and maintain deleterious pulmonary infections. Theoretically, eradication of the sinus bacteria should reduce the frequency of lung infections and thereby reduce pulmonary morbidity. This article addressed whether bacteria in CF sinuses are eligible for eradication by sinus surgery and postoperative treatment.

Original language	English
Journal	American Journal of Rhinology & Allergy
Volume	27
Issue number	1
Pages (from-to)	e1-4
ISSN	1945-8924
DOIs	https://doi.org/10.2500/ajra.2013.27.3829
Publication status	Published - Jan 2013

Keywords

Achromobacter denitrificans
Adolescent
Adult
Burkholderia
Burkholderia Infections
Child
Chronic Disease
Colistin
Cystic Fibrosis
Female
Follow-Up Studies
Gram-Negative Bacterial Infections
Humans
Male
Middle Aged
Nasal Lavage
Paranasal Sinuses
Prospective Studies
Pseudomonas Infections
Pseudomonas aeruginosa
Rhinitis
Sinusitis
Treatment Outcome
Young Adult

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10.2500/ajra.2013.27.3829

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title = "The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis",

abstract = "Most patients with cystic fibrosis (CF) have chronic rhinosinusitis; their sinuses are often colonized with bacteria that can initiate and maintain deleterious pulmonary infections. Theoretically, eradication of the sinus bacteria should reduce the frequency of lung infections and thereby reduce pulmonary morbidity. This article addressed whether bacteria in CF sinuses are eligible for eradication by sinus surgery and postoperative treatment.",

keywords = "Achromobacter denitrificans, Adolescent, Adult, Burkholderia, Burkholderia Infections, Child, Chronic Disease, Colistin, Cystic Fibrosis, Female, Follow-Up Studies, Gram-Negative Bacterial Infections, Humans, Male, Middle Aged, Nasal Lavage, Paranasal Sinuses, Prospective Studies, Pseudomonas Infections, Pseudomonas aeruginosa, Rhinitis, Sinusitis, Treatment Outcome, Young Adult",

author = "Kasper Aanaes and {von Buchwald}, Christian and Thomas Hjuler and Marianne Skov and Mikkel Alanin and Johansen, {Helle Krogh}",

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T1 - The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis

AU - Aanaes, Kasper

AU - von Buchwald, Christian

AU - Hjuler, Thomas

AU - Skov, Marianne

AU - Alanin, Mikkel

AU - Johansen, Helle Krogh

PY - 2013/1

Y1 - 2013/1

N2 - Most patients with cystic fibrosis (CF) have chronic rhinosinusitis; their sinuses are often colonized with bacteria that can initiate and maintain deleterious pulmonary infections. Theoretically, eradication of the sinus bacteria should reduce the frequency of lung infections and thereby reduce pulmonary morbidity. This article addressed whether bacteria in CF sinuses are eligible for eradication by sinus surgery and postoperative treatment.

AB - Most patients with cystic fibrosis (CF) have chronic rhinosinusitis; their sinuses are often colonized with bacteria that can initiate and maintain deleterious pulmonary infections. Theoretically, eradication of the sinus bacteria should reduce the frequency of lung infections and thereby reduce pulmonary morbidity. This article addressed whether bacteria in CF sinuses are eligible for eradication by sinus surgery and postoperative treatment.

KW - Achromobacter denitrificans

KW - Adolescent

KW - Adult

KW - Burkholderia

KW - Burkholderia Infections

KW - Child

KW - Chronic Disease

KW - Colistin

KW - Cystic Fibrosis

KW - Female

KW - Follow-Up Studies

KW - Gram-Negative Bacterial Infections

KW - Humans

KW - Male

KW - Middle Aged

KW - Nasal Lavage

KW - Paranasal Sinuses

KW - Prospective Studies

KW - Pseudomonas Infections

KW - Pseudomonas aeruginosa

KW - Rhinitis

KW - Sinusitis

KW - Treatment Outcome

KW - Young Adult

U2 - 10.2500/ajra.2013.27.3829

DO - 10.2500/ajra.2013.27.3829

M3 - Journal article

C2 - 23406585

SN - 1945-8924

VL - 27

SP - e1-4

JO - American Journal of Rhinology & Allergy

JF - American Journal of Rhinology & Allergy

IS - 1

ER -

The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis

Abstract

Keywords

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