The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

Lasse Bremholm; Mads Hornum; Ulrik B Andersen; Bolette Hartmann; Jens Juul Holst; Palle Bekker Jeppesen

doi:10.1016/j.regpep.2011.03.003

The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

Lasse Bremholm, Mads Hornum, Ulrik B Andersen, Bolette Hartmann, Jens Juul Holst, Palle Bekker Jeppesen

Department of Clinical Physiology and Nuclear Medicine

94 Citations (Scopus)

Abstract

Exogenous Glucagon-Like Peptide-2 (GLP-2) treatment improves intestinal wet weight absorption in short bowel syndrome (SBS) patients. In healthy subjects, administration of GLP-2 increases small intestinal blood flow. The aim of the study was to evaluate the effect of GLP-2 on mesenteric blood flow and dynamic changes in cardiac parameters in SBS patients with jejunostomy and varying length of remnant small intestine.

Original language	English
Journal	Regulatory Peptides
Volume	168
Issue number	1-3
Pages (from-to)	32-8
Number of pages	7
ISSN	0167-0115
DOIs	https://doi.org/10.1016/j.regpep.2011.03.003
Publication status	Published - 7 Jun 2011

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10.1016/j.regpep.2011.03.003

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abstract = "Exogenous Glucagon-Like Peptide-2 (GLP-2) treatment improves intestinal wet weight absorption in short bowel syndrome (SBS) patients. In healthy subjects, administration of GLP-2 increases small intestinal blood flow. The aim of the study was to evaluate the effect of GLP-2 on mesenteric blood flow and dynamic changes in cardiac parameters in SBS patients with jejunostomy and varying length of remnant small intestine.",

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AU - Andersen, Ulrik B

AU - Hartmann, Bolette

AU - Holst, Jens Juul

AU - Jeppesen, Palle Bekker

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AB - Exogenous Glucagon-Like Peptide-2 (GLP-2) treatment improves intestinal wet weight absorption in short bowel syndrome (SBS) patients. In healthy subjects, administration of GLP-2 increases small intestinal blood flow. The aim of the study was to evaluate the effect of GLP-2 on mesenteric blood flow and dynamic changes in cardiac parameters in SBS patients with jejunostomy and varying length of remnant small intestine.

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DO - 10.1016/j.regpep.2011.03.003

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The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

Abstract

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