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The effect of antidepressants on brain volume

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  1. Depression kan forværre handikaps, når man har sclerose

    Research output: Contribution to journalContribution to newspaper - Comment/debateCommunication

  2. The risks of selective serotonin reuptake inhibitor intake in pregnancy

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  3. Electroconvulsive Therapy Practice in the Kingdom of Denmark: A Nationwide Register- and Questionnaire-Based Study

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  4. Nyt studie: Patienter med tegn på depression bliver ikke mindre depressive af SSRI-medicin

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  5. Færre bliver bæltefikseret: Liselotte bliver masseret af en fysioterapeut, inden hun mister kontrollen

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In this review, we summarise all studies of patients with depression, who have been examined by MRI before and after treatment with antidepressants. None of the studies showed any signs of damage to the brain tissue after treatment. On the contrary, most studies showed increases in hippocampal volume and prefrontal cortices in parallel with response or remission after treatment. As depression in several meta-analyses has been shown to double the risk for dementia, this could have important implications for preventive measures, because, for instance, hippocampal atrophy is seen in both diseases.

Translated title of the contributionThe effect of antidepressants on brain volume
Original languageDanish
JournalUgeskrift for Laeger
Volume181
Issue number38
ISSN0041-5782
Publication statusPublished - 16 Sep 2019

ID: 58130219