Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

The economic impact of prevention, monitoring and treatment strategies for iodine deficiency disorders in Germany

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Cholecystokinin and the hormone concept

    Research output: Contribution to journalReviewpeer-review

  2. Determining minimal important change for the thyroid-related quality of life questionnaire ThyPRO

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Free testosterone and cardiometabolic parameters in men: comparison of algorithms

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Plasma levels of glucagon but not GLP-1 are elevated in response to inflammation in humans

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Influence of educational level on test and treatment for incident hypothyroidism

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Symptoms and biomarkers associated with undiagnosed celiac seropositivity

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Benefits and Harms of a Prevention Program for Iodine Deficiency Disorders - Predictions of the Decision-Analytic EUthyroid Model

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Monika Schaffner
  • Ursula Rochau
  • Nikolai Mühlberger
  • Annette Conrads-Frank
  • Vjollca Qerimi Rushaj
  • Gaby Sroczynski
  • Eftychia Koukkou
  • Betina Heinsbaek Thuesen
  • Henry Völzke
  • Wilhelm Oberaigner
  • Uwe Siebert
View graph of relations

Objective: More than 30% of the German population suffers from mild to moderate iodine deficiency causing goiter and other iodine deficiency disorders (IDDs). The economic burden of iodine deficiency is still unclear. We aimed to assess costs for prevention, monitoring and treatment of IDDs in Germany.

Design: We performed a comprehensive cost analysis.

Methods: We assessed direct medical costs and direct non-medical costs for inpatient and outpatient care of IDDs and costs for productivity loss due to the absence of work in 2018. Additionally, we calculated total costs for an IDD prevention program comprising universal salt iodization (USI). We performed threshold analyses projecting how many cases of IDDs or related treatments would need to be avoided for USI to be cost-saving.

Results: Annual average costs per case in the year of diagnosis were € 211 for goiter/thyroid nodules; € 308 for hyperthyroidism; and € 274 for hypothyroidism. Average one-time costs for thyroidectomy were € 4184 and € 3118 for radioiodine therapy. Average costs for one case of spontaneous abortion were € 916. Annual costs of intellectual disability were € 14,202. In the German population, total annual costs for USI would amount to 8 million Euro. To be cost-saving, USI would need to prevent, for example, 37,900 cases of goiter/thyroid nodules.

Conclusion: USI potentially saves costs, if a minimum amount of IDDs per year could be avoided. In order to recommend the implementation of USI, a full health-economic evaluation including a comprehensive benefit-harm assessment is needed.

Original languageEnglish
JournalEndocrine Connections
Volume10
Issue number1
Pages (from-to)1-12
Number of pages12
ISSN2049-3614
DOIs
Publication statusPublished - Jan 2021

    Research areas

  • Cost analysis, Iodine deficiency, Prevention program, Resource analysis, Salt iodization, Thyroid disorders

ID: 61866595