The danish protease inhibitor study: a randomized study comparing the virological efficacy of 3 protease inhibitor-containing regimens for the treatment of human immunodeficiency virus type 1 infection

T L Katzenstein, O Kirk, C Pedersen, J D Lundgren, H Nielsen, N Obel, C Nielsen, Lars Reinhardt Mathiesen, J Gerstoft

25 Citations (Scopus)

Abstract

The Danish Protease Inhibitor (PI) Study has enrolled 318 human immunodeficiency virus (HIV)-infected, PI-naive patients for the purpose of comparing 3 PI-containing regimens for the treatment of HIV infection. The regimens include 2 nucleoside analogues in combination with indinavir (Idr), ritonavir (Rtv), or Rtv and saquinavir (Rtv/Sqv). Similar percentages of patients in the 3 study arms achieved reduced levels (
Original languageEnglish
JournalJournal of Infectious Diseases
Volume182
Issue number3
Pages (from-to)744-50
Number of pages6
ISSN0022-1899
DOIs
Publication statusPublished - 2000

Keywords

  • Adolescent
  • Adult
  • CD4 Lymphocyte Count
  • Drug Therapy, Combination
  • Female
  • HIV Infections
  • HIV Protease Inhibitors
  • HIV-1
  • Humans
  • Indinavir
  • Male
  • Ritonavir
  • Saquinavir
  • Viral Load

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