The Best Bypass Surgery Trial: rationale and design of a randomized clinical trial with blinded outcome assessment of conventional versus off-pump coronary artery bypass grafting

Christian H Møller; Birte Østergaard Jensen; Christian Gluud; Mario J Perko; Jens T Lund; Lars Willy Andersen; Jan Kyst Madsen; Pia Hughes; Daniel A Steinbrüchel

doi:10.1016/j.cct.2006.11.002

The Best Bypass Surgery Trial: rationale and design of a randomized clinical trial with blinded outcome assessment of conventional versus off-pump coronary artery bypass grafting

Christian H Møller
, Birte Østergaard Jensen
, Christian Gluud
, Mario J Perko
, Jens T Lund
, Lars Willy Andersen
, Jan Kyst Madsen
, Pia Hughes
, Daniel A Steinbrüchel

Copenhagen Trial Unit

11 Citations (Scopus)

Abstract

Recent trials suggest that off-pump coronary artery bypass grafting (OPCAB) reduces the risk of mortality and morbidity compared with conventional coronary artery bypass grafting (CCAB) using cardiopulmonary bypass. Patients with a moderate- to high-risk of complications after CCAB may have additional benefit from OPCAB.

Original language	English
Journal	Contemporary Clinical Trials
Volume	28
Issue number	4
Pages (from-to)	540-7
Number of pages	8
ISSN	1551-7144
DOIs	https://doi.org/10.1016/j.cct.2006.11.002
Publication status	Published - Jul 2007

Keywords

Aged
Cardiopulmonary Bypass
Cause of Death
Coronary Angiography
Coronary Artery Bypass
Coronary Artery Bypass, Off-Pump
Denmark
Endpoint Determination
Female
Follow-Up Studies
Humans
Male
Middle Aged
Outcome Assessment (Health Care)
Postoperative Complications
Quality of Life
Research Design
Risk Factors
Single-Blind Method

Access to Document

10.1016/j.cct.2006.11.002

Cite this

Møller, C. H., Jensen, B. Ø., Gluud, C., Perko, M. J., Lund, J. T., Andersen, L. W., Madsen, J. K., Hughes, P., & Steinbrüchel, D. A. (2007). The Best Bypass Surgery Trial: rationale and design of a randomized clinical trial with blinded outcome assessment of conventional versus off-pump coronary artery bypass grafting. Contemporary Clinical Trials, 28(4), 540-7. https://doi.org/10.1016/j.cct.2006.11.002

The Best Bypass Surgery Trial: rationale and design of a randomized clinical trial with blinded outcome assessment of conventional versus off-pump coronary artery bypass grafting. / Møller, Christian H; Jensen, Birte Østergaard; Gluud, Christian et al.
In: Contemporary Clinical Trials, Vol. 28, No. 4, 07.2007, p. 540-7.

Research output: Contribution to journal › Journal article › Research › peer-review

Møller, CH, Jensen, BØ, Gluud, C, Perko, MJ, Lund, JT, Andersen, LW, Madsen, JK, Hughes, P & Steinbrüchel, DA 2007, 'The Best Bypass Surgery Trial: rationale and design of a randomized clinical trial with blinded outcome assessment of conventional versus off-pump coronary artery bypass grafting', Contemporary Clinical Trials, vol. 28, no. 4, pp. 540-7. https://doi.org/10.1016/j.cct.2006.11.002

@article{f01fe1d3b68b4799ac4535b1768c4ace,

title = "The Best Bypass Surgery Trial: rationale and design of a randomized clinical trial with blinded outcome assessment of conventional versus off-pump coronary artery bypass grafting",

abstract = "Recent trials suggest that off-pump coronary artery bypass grafting (OPCAB) reduces the risk of mortality and morbidity compared with conventional coronary artery bypass grafting (CCAB) using cardiopulmonary bypass. Patients with a moderate- to high-risk of complications after CCAB may have additional benefit from OPCAB.",

keywords = "Aged, Cardiopulmonary Bypass, Cause of Death, Coronary Angiography, Coronary Artery Bypass, Coronary Artery Bypass, Off-Pump, Denmark, Endpoint Determination, Female, Follow-Up Studies, Humans, Male, Middle Aged, Outcome Assessment (Health Care), Postoperative Complications, Quality of Life, Research Design, Risk Factors, Single-Blind Method",

author = "M{\o}ller, \{Christian H\} and Jensen, \{Birte {\O}stergaard\} and Christian Gluud and Perko, \{Mario J\} and Lund, \{Jens T\} and Andersen, \{Lars Willy\} and Madsen, \{Jan Kyst\} and Pia Hughes and Steinbr{\"u}chel, \{Daniel A\}",

year = "2007",

month = jul,

doi = "10.1016/j.cct.2006.11.002",

language = "English",

volume = "28",

pages = "540--7",

journal = "Contemporary Clinical Trials",

issn = "1551-7144",

publisher = "Elsevier Inc.",

number = "4",

}

TY - JOUR

T1 - The Best Bypass Surgery Trial

T2 - rationale and design of a randomized clinical trial with blinded outcome assessment of conventional versus off-pump coronary artery bypass grafting

AU - Møller, Christian H

AU - Jensen, Birte Østergaard

AU - Gluud, Christian

AU - Perko, Mario J

AU - Lund, Jens T

AU - Andersen, Lars Willy

AU - Madsen, Jan Kyst

AU - Hughes, Pia

AU - Steinbrüchel, Daniel A

PY - 2007/7

Y1 - 2007/7

N2 - Recent trials suggest that off-pump coronary artery bypass grafting (OPCAB) reduces the risk of mortality and morbidity compared with conventional coronary artery bypass grafting (CCAB) using cardiopulmonary bypass. Patients with a moderate- to high-risk of complications after CCAB may have additional benefit from OPCAB.

AB - Recent trials suggest that off-pump coronary artery bypass grafting (OPCAB) reduces the risk of mortality and morbidity compared with conventional coronary artery bypass grafting (CCAB) using cardiopulmonary bypass. Patients with a moderate- to high-risk of complications after CCAB may have additional benefit from OPCAB.

KW - Aged

KW - Cardiopulmonary Bypass

KW - Cause of Death

KW - Coronary Angiography

KW - Coronary Artery Bypass

KW - Coronary Artery Bypass, Off-Pump

KW - Denmark

KW - Endpoint Determination

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Outcome Assessment (Health Care)

KW - Postoperative Complications

KW - Quality of Life

KW - Research Design

KW - Risk Factors

KW - Single-Blind Method

U2 - 10.1016/j.cct.2006.11.002

DO - 10.1016/j.cct.2006.11.002

M3 - Journal article

C2 - 17188581

SN - 1551-7144

VL - 28

SP - 540

EP - 547

JO - Contemporary Clinical Trials

JF - Contemporary Clinical Trials

IS - 4

ER -

The Best Bypass Surgery Trial: rationale and design of a randomized clinical trial with blinded outcome assessment of conventional versus off-pump coronary artery bypass grafting

Abstract

Keywords

Access to Document

Fingerprint

Cite this