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The autism diagnostic observation schedule: Patterns in individuals with anorexia nervosa

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@article{5997b0c3fda4426db4f7dec768c0fb71,
title = "The autism diagnostic observation schedule: Patterns in individuals with anorexia nervosa",
abstract = "OBJECTIVE: Studies have used the Autism Diagnostic Observation Schedule (the ADOS-2) in individuals with anorexia nervosa (AN), but the patterns of scores have not been assessed. We examined which subset of the ADOS-2 items best discriminate individuals with AN from healthy controls (HC), and assessed the potential clustering of AN participants based on different profiles of the ADOS-2 item scores.METHOD: We combined datasets from two previous studies, and (a) compared mean ranks between young AN participants (N = 118) and HC (N = 42), (ii) replicated the item selection procedure of the existing ADOS-2 algorithm to assess sensitivity of items in the AN group, and (c) applied a two-step clustering analysis in the AN group (N = 149).RESULTS: AN participants displayed significantly higher mean ranks than HC participants in five of 32 items. All five items are part of the existing ADOS-2 algorithm. We found two clusters of AN participants; one representing normal social behaviour, comprising 68% of the individuals with AN, and one representing less efficient social behaviour, comprising 32% of individuals with AN.CONCLUSIONS: The items comprising the social affective cluster of the existing ADOS-2 algorithm are well suited to assess difficulties with social functioning in individuals with AN.",
keywords = "anorexia nervosa, autism spectrum disorder, psychometrics, social functioning",
author = "Mette Bentz and Heather Westwood and Jepsen, {Jens Richardt M{\o}llegaard} and Plessen, {Kerstin Jessica} and Kate Tchanturia",
note = "{\textcopyright} 2020 John Wiley & Sons, Ltd and Eating Disorders Association.",
year = "2020",
month = sep,
doi = "10.1002/erv.2757",
language = "English",
volume = "28",
pages = "571--579",
journal = "European Eating Disorders Review",
issn = "1072-4133",
publisher = "John/Wiley & Sons Ltd",
number = "5",

}

RIS

TY - JOUR

T1 - The autism diagnostic observation schedule

T2 - Patterns in individuals with anorexia nervosa

AU - Bentz, Mette

AU - Westwood, Heather

AU - Jepsen, Jens Richardt Møllegaard

AU - Plessen, Kerstin Jessica

AU - Tchanturia, Kate

N1 - © 2020 John Wiley & Sons, Ltd and Eating Disorders Association.

PY - 2020/9

Y1 - 2020/9

N2 - OBJECTIVE: Studies have used the Autism Diagnostic Observation Schedule (the ADOS-2) in individuals with anorexia nervosa (AN), but the patterns of scores have not been assessed. We examined which subset of the ADOS-2 items best discriminate individuals with AN from healthy controls (HC), and assessed the potential clustering of AN participants based on different profiles of the ADOS-2 item scores.METHOD: We combined datasets from two previous studies, and (a) compared mean ranks between young AN participants (N = 118) and HC (N = 42), (ii) replicated the item selection procedure of the existing ADOS-2 algorithm to assess sensitivity of items in the AN group, and (c) applied a two-step clustering analysis in the AN group (N = 149).RESULTS: AN participants displayed significantly higher mean ranks than HC participants in five of 32 items. All five items are part of the existing ADOS-2 algorithm. We found two clusters of AN participants; one representing normal social behaviour, comprising 68% of the individuals with AN, and one representing less efficient social behaviour, comprising 32% of individuals with AN.CONCLUSIONS: The items comprising the social affective cluster of the existing ADOS-2 algorithm are well suited to assess difficulties with social functioning in individuals with AN.

AB - OBJECTIVE: Studies have used the Autism Diagnostic Observation Schedule (the ADOS-2) in individuals with anorexia nervosa (AN), but the patterns of scores have not been assessed. We examined which subset of the ADOS-2 items best discriminate individuals with AN from healthy controls (HC), and assessed the potential clustering of AN participants based on different profiles of the ADOS-2 item scores.METHOD: We combined datasets from two previous studies, and (a) compared mean ranks between young AN participants (N = 118) and HC (N = 42), (ii) replicated the item selection procedure of the existing ADOS-2 algorithm to assess sensitivity of items in the AN group, and (c) applied a two-step clustering analysis in the AN group (N = 149).RESULTS: AN participants displayed significantly higher mean ranks than HC participants in five of 32 items. All five items are part of the existing ADOS-2 algorithm. We found two clusters of AN participants; one representing normal social behaviour, comprising 68% of the individuals with AN, and one representing less efficient social behaviour, comprising 32% of individuals with AN.CONCLUSIONS: The items comprising the social affective cluster of the existing ADOS-2 algorithm are well suited to assess difficulties with social functioning in individuals with AN.

KW - anorexia nervosa

KW - autism spectrum disorder

KW - psychometrics

KW - social functioning

UR - http://www.scopus.com/inward/record.url?scp=85088809393&partnerID=8YFLogxK

U2 - 10.1002/erv.2757

DO - 10.1002/erv.2757

M3 - Journal article

C2 - 32729156

VL - 28

SP - 571

EP - 579

JO - European Eating Disorders Review

JF - European Eating Disorders Review

SN - 1072-4133

IS - 5

ER -

ID: 60590124