The Aging Prostate Is Never "Normal": Implications from the Genomic Characterization of Multifocal Prostate Cancers

Thorsten Schlomm; Joachim Weischenfeldt; Jan Korbel; Guido Sauter

doi:10.1016/j.eururo.2015.04.012

The Aging Prostate Is Never "Normal": Implications from the Genomic Characterization of Multifocal Prostate Cancers

Thorsten Schlomm^*, Joachim Weischenfeldt, Jan Korbel, Guido Sauter

^*Corresponding author for this work

3 Citations (Scopus)

Abstract

Take Home Message We argue against the recently published statement that tumor-specific molecular alterations found in "normal" prostate tissue from cancer patients challenge focal therapy approaches that only target a visible cancer lesion and not the adjacent molecular field.

Original language	English
Article number	6171
Journal	European Urology
Volume	68
Issue number	3
Pages (from-to)	348-350
Number of pages	3
ISSN	0302-2838
DOIs	https://doi.org/10.1016/j.eururo.2015.04.012
Publication status	Published - 1 Jan 2015
Externally published	Yes

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10.1016/j.eururo.2015.04.012

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title = "The Aging Prostate Is Never {"}Normal{"}: Implications from the Genomic Characterization of Multifocal Prostate Cancers",

abstract = "Take Home Message We argue against the recently published statement that tumor-specific molecular alterations found in {"}normal{"} prostate tissue from cancer patients challenge focal therapy approaches that only target a visible cancer lesion and not the adjacent molecular field.",

author = "Thorsten Schlomm and Joachim Weischenfeldt and Jan Korbel and Guido Sauter",

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AU - Schlomm, Thorsten

AU - Weischenfeldt, Joachim

AU - Korbel, Jan

AU - Sauter, Guido

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Take Home Message We argue against the recently published statement that tumor-specific molecular alterations found in "normal" prostate tissue from cancer patients challenge focal therapy approaches that only target a visible cancer lesion and not the adjacent molecular field.

AB - Take Home Message We argue against the recently published statement that tumor-specific molecular alterations found in "normal" prostate tissue from cancer patients challenge focal therapy approaches that only target a visible cancer lesion and not the adjacent molecular field.

UR - https://www.scopus.com/pages/publications/84940592103

U2 - 10.1016/j.eururo.2015.04.012

DO - 10.1016/j.eururo.2015.04.012

M3 - Journal article

C2 - 25913065

AN - SCOPUS:84940592103

SN - 0302-2838

VL - 68

SP - 348

EP - 350

JO - European Urology

JF - European Urology

IS - 3

M1 - 6171

ER -

The Aging Prostate Is Never "Normal": Implications from the Genomic Characterization of Multifocal Prostate Cancers

Abstract

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