Terapeutiske vacciner er et nyt behandlingsprincip ved kastrationsresistent prostatacancer

Sissal Sigmundsdóttir  Djurhuus; Klaus Brasso; Kasper Drimer Berg; Peter Iversen; Martin Andreas Røder

Terapeutiske vacciner er et nyt behandlingsprincip ved kastrationsresistent prostatacancer

Translated title of the contribution: Therapeutic vaccines is a novel approach in castration-resistant prostate cancer treatment

Sissal Sigmundsdóttir Djurhuus, Klaus Brasso, Kasper Drimer Berg, Peter Iversen, Martin Andreas Røder

Abstract

Castration-resistant prostate cancer (CRPC) is defined as tumour progression despite castrate levels of serum testosterone. During the past decade a number of new therapies, including chemotherapy and novel endocrine agents have been approved for CRPC treatment. The continued need for new effective drugs in CRPC has led to development of a novel therapeutic approach in CRPC treatment. Therapeutic vaccines activate the immune system to kill prostate cancer cells. This review describes recent pivotal phase 2 and 3 trials of CRPC vaccines and discusses the impact on future CRPC management.

Translated title of the contribution	Therapeutic vaccines is a novel approach in castration-resistant prostate cancer treatment
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	177
Issue number	20
Pages (from-to)	V11140628
ISSN	0041-5782
Publication status	Published - 11 May 2015

Cite this

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title = "Terapeutiske vacciner er et nyt behandlingsprincip ved kastrationsresistent prostatacancer",

abstract = "Castration-resistant prostate cancer (CRPC) is defined as tumour progression despite castrate levels of serum testosterone. During the past decade a number of new therapies, including chemotherapy and novel endocrine agents have been approved for CRPC treatment. The continued need for new effective drugs in CRPC has led to development of a novel therapeutic approach in CRPC treatment. Therapeutic vaccines activate the immune system to kill prostate cancer cells. This review describes recent pivotal phase 2 and 3 trials of CRPC vaccines and discusses the impact on future CRPC management.",

author = "Djurhuus, {Sissal Sigmundsd{\'o}ttir} and Klaus Brasso and Berg, {Kasper Drimer} and Peter Iversen and R{\o}der, {Martin Andreas}",

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AU - Djurhuus, Sissal Sigmundsdóttir

AU - Brasso, Klaus

AU - Berg, Kasper Drimer

AU - Iversen, Peter

AU - Røder, Martin Andreas

PY - 2015/5/11

Y1 - 2015/5/11

N2 - Castration-resistant prostate cancer (CRPC) is defined as tumour progression despite castrate levels of serum testosterone. During the past decade a number of new therapies, including chemotherapy and novel endocrine agents have been approved for CRPC treatment. The continued need for new effective drugs in CRPC has led to development of a novel therapeutic approach in CRPC treatment. Therapeutic vaccines activate the immune system to kill prostate cancer cells. This review describes recent pivotal phase 2 and 3 trials of CRPC vaccines and discusses the impact on future CRPC management.

AB - Castration-resistant prostate cancer (CRPC) is defined as tumour progression despite castrate levels of serum testosterone. During the past decade a number of new therapies, including chemotherapy and novel endocrine agents have been approved for CRPC treatment. The continued need for new effective drugs in CRPC has led to development of a novel therapeutic approach in CRPC treatment. Therapeutic vaccines activate the immune system to kill prostate cancer cells. This review describes recent pivotal phase 2 and 3 trials of CRPC vaccines and discusses the impact on future CRPC management.

M3 - Tidsskriftartikel

C2 - 25967247

VL - 177

SP - V11140628

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 20

ER -

Terapeutiske vacciner er et nyt behandlingsprincip ved kastrationsresistent prostatacancer

Abstract

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