Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Ten-year mortality is increased after hospitalization for atopic dermatitis compared with the general population, but reduced compared with psoriasis

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Chronologic order of appearance of immune-mediated inflammatory diseases relative to diagnosis of psoriasis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Using a metallic ink pen to assist in the demarcation of skin lesions under reflectance confocal microscopy

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Factors associated with patient-reported importance of skin clearance among adults with psoriasis and atopic dermatitis

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Estimating CDKN2A mutation carrier probability among global familial melanoma cases using GenoMELPREDICT

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Drug survival of secukinumab and ixekizumab for moderate-to-severe plaque psoriasis

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Incidence of Ischemic Stroke in Individuals With and Without Aortic Valve Stenosis: A Danish Retrospective Cohort Study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Cardiovascular complications in patients with total cavopulmonary connection: A nationwide cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Favorable five-year outcomes for heart failure diagnosed in younger patients without severe comorbidity

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Quality of life and the associated risk of all-cause mortality in nonischemic heart failure

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Does type 2 diabetes confer higher relative rates of cardiovascular events in women compared with men?

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

BACKGROUND: Psoriasis and atopic dermatitis (AD) are chronic inflammatory skin disorders. Mortality is increased in psoriasis, yet no studies on mortality in AD are currently available.

OBJECTIVE: We investigated 10-year mortality after hospitalization for AD compared with psoriasis and the general population.

METHODS: Between 1996 and 2002 all Danes aged 18 years or older with a first-time hospitalization as a result of AD or psoriasis and AD-matched healthy control subjects were examined in nationwide registers. Multivariable (adjusted for age, sex, socioeconomic status, Charlson Comorbidity Index score, smoking, and medication) hazard ratios were estimated by Cox regression.

RESULTS: The study comprised 576 and 951 hospitalized patients with AD and psoriasis, respectively, with a maximum follow-up time of 10 years. During the study period, there were 65 and 286 deaths among patients with AD and psoriasis. Risk of death was decreased in patients with AD versus psoriasis (hazard ratio 0.75; 95% confidence interval 0.57-1.00), but higher than in general population control subjects (n = 5760) (hazard ratio 1.71; 95% confidence interval 1.20-2.44). Patients hospitalized with AD died on average 8.3 years younger than control subjects.

LIMITATIONS: Lifestyle may have affected the risk.

CONCLUSIONS: The 10-year mortality was significantly lower after hospitalization for AD compared with psoriasis, but increased when compared with the general population.

Original languageEnglish
JournalJournal of the American Academy of Dermatology
Volume76
Issue number1
Pages (from-to)98-105
ISSN0190-9622
DOIs
Publication statusPublished - Jan 2017

ID: 49151945